2-phenylethynyl-4-trifluoromethoxyaniline

Base Information

Chemical Name:2-phenylethynyl-4-trifluoromethoxyaniline
CAS No.:1181455-52-6
Molecular Formula:C₁₅H₁₀F₃NO
Molecular Weight:277.246
Hs Code.:

Synonyms:2-phenylethynyl-4-trifluoromethoxyaniline

Suppliers and Price of 2-phenylethynyl-4-trifluoromethoxyaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2-phenylethynyl-4-trifluoromethoxyaniline

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of 2-phenylethynyl-4-trifluoromethoxyaniline

There total 2 articles about 2-phenylethynyl-4-trifluoromethoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 536-74-3
phenylacetylene

: 175278-17-8
2-bromo-4-trifluoromethoxyaniline

: 1181455-52-6
2-phenylethynyl-4-trifluoromethoxyaniline

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; ethanolamine; In tetrahydrofuran; water; for 19h; Inert atmosphere; Reflux;
DOI:10.1021/ol901317j

Reference yield:

: 845866-79-7
2-iodo-4-(trifluoromethoxy)aniline

: 536-74-3
phenylacetylene

: 1181455-52-6
2-phenylethynyl-4-trifluoromethoxyaniline

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 20 ℃; Inert atmosphere; Schlenk technique;
DOI:10.1002/anie.201913656

Reference yield: 31.0%

: 1181455-52-6
2-phenylethynyl-4-trifluoromethoxyaniline

: 906774-22-9
2-phenyl-5-(trifluoromethoxy)-1H-indole

Guidance literature:: With potassium tert-butylate; In 1-methyl-pyrrolidin-2-one; at 100 ℃; for 12h; Schlenk technique;
DOI:10.1002/anie.201913656