Technology Process of C16H15N3O3
There total 1 articles about C16H15N3O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium t-butanolate;
palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl;
In
1,2-dimethoxyethane;
for 5h;
Product distribution / selectivity;
Inert atmosphere;
Reflux;
- Guidance literature:
-
C16H15N3O3;
With
trichlorophosphate;
at 80 ℃;
for 0.666667h;
With
potassium carbonate;
In
water;
Product distribution / selectivity;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: trichlorophosphate / 0.67 h / 80 °C
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.33 h / 5 °C / Inert atmosphere
2.2: 1.83 h / 5 - 20 °C
3.1: potassium phosphate / tris-(dibenzylideneacetone)dipalladium(0); XPhos / 1,4-dioxane; water / 80 °C / Inert atmosphere
4.1: hydrogenchloride; water / 1,4-dioxane / 70 °C
4.2: Cooling with ice
5.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 °C
5.2: 4 h / 20 °C
With
hydrogenchloride; potassium phosphate; water; sodium hydride; trichlorophosphate;
tris-(dibenzylideneacetone)dipalladium(0); XPhos;
In
1,4-dioxane; water; N,N-dimethyl-formamide; mineral oil;