2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-6-methyl-pyrimidin-4-ol

Base Information

Chemical Name:2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-6-methyl-pyrimidin-4-ol
CAS No.:1185018-57-8
Molecular Formula:C₁₆H₁₇N₅O₂
Molecular Weight:311.343
Hs Code.:

Synonyms:2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-6-methyl-pyrimidin-4-ol

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Chemical Property of 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-6-methyl-pyrimidin-4-ol

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Technology Process of 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-6-methyl-pyrimidin-4-ol

There total 1 articles about 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-6-methyl-pyrimidin-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)guanidine dinitrate

: 141-97-9
ethyl acetoacetate

: 1185018-57-8
2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-6-methyl-pyrimidin-4-ol

Guidance literature:: 1-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)guanidine dinitrate; ethyl acetoacetate; With sodium ethanolate; In methanol; at 20 ℃; Inert atmosphere; Reflux;

With hydrogenchloride; water; In methanol; pH=7;

Reference yield: 100.0%

: 1185018-57-8
2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-6-methyl-pyrimidin-4-ol

: 1185013-72-2
(4-chloro-6-methyl-pyrimidin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine

Guidance literature:: 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-6-methyl-pyrimidin-4-ol; With trichlorophosphate; for 2h; Reflux;

With ammonia; In water; Cooling with ice;