(S)-2,6-Bis-benzyloxycarbonylamino-hexanoic acid (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester

Base Information

• Chemical Name: (S)-2,6-Bis-benzyloxycarbonylamino-hexanoic acid (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester
• CAS No.: 173410-91-8
• Molecular Formula: C₃₂H₃₇N₇O₉
• Molecular Weight: 663.687
• Mol file: 173410-91-8.mol

Synonyms:(S)-2,6-Bis-benzyloxycarbonylamino-hexanoic acid (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester

Chemical Property of (S)-2,6-Bis-benzyloxycarbonylamino-hexanoic acid (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2,6-Bis-benzyloxycarbonylamino-hexanoic acid (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester

There total 1 articles about (S)-2,6-Bis-benzyloxycarbonylamino-hexanoic acid (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

N,N'-di-[(phenylmethoxy)carbonyl]-L-lysine (405-39-0) + 2'-Deoxyguanosine (961-07-9) → (S)-2,6-Bis-benzyloxycarbonylamino-hexanoic acid (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl ester + (S)-2,6-Bis-benzyloxycarbonylamino-hexanoic acid (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester (173410-91-8)

Guidance literature:

With tributyl-amine; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 23 ℃;

DOI:10.1021/ja00155a005

upstream raw materials:

N,N'-di-[(phenylmethoxy)carbonyl]-L-lysine

2'-Deoxyguanosine