C₁₁H₁₀NSO₂F

Base Information

• Chemical Name: C₁₁H₁₀NSO₂F
• CAS No.: 949897-58-9
• Molecular Formula: C₁₁H₁₀FNO₂S
• Molecular Weight: 239.27
• Mol file: 949897-58-9.mol

Synonyms:C₁₁H₁₀NSO₂F

Chemical Property of C₁₁H₁₀NSO₂F

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₁H₁₀NSO₂F

There total 3 articles about C₁₁H₁₀NSO₂F which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

3-(2-phenylacetyl)thiazolidin-2-one → C11H10NSO2F (949897-58-9)

Guidance literature:

With 2,6-dimethylpyridine; nickel(II) perchlorate hexahydrate; 1,1,1,3',3',3'-hexafluoro-propanol; N-fluorobis(benzenesulfon)imide; (R,R)-4,6-dibenzofurandiyl-2,2'-bis(4-phenyloxazoline); In dichloromethane; at -60 ℃; for 48h; optical yield given as %ee; enantioselective reaction; Molecular sieve;

DOI:10.1002/asia.200900164

Reference yield:

C11H11NSO2SiC6H14 → C11H10NSO2F + C11H10NSO2F (949897-58-9)

Guidance literature:

With N-fluorobis(benzenesulfon)imide; chiral binap-based nickel complex; In ⁽²⁾H₈-toluene; at -20 ℃; for 24h; Title compound not separated from byproducts.;

DOI:10.1002/anie.200701071

Reference yield:

3-(2-phenylacetyl)thiazolidin-2-one → C11H10NSO2F + C11H10NSO2F (949897-58-9)

Guidance literature:

3-(2-phenylacetyl)thiazolidin-2-one; With triethylsilyl trifluoromethyl sulfonate; N-fluorobis(benzenesulfon)imide; chiral binap-based nickel complex; In toluene; at -20 ℃; for 0.166667h;

With 2,6-dimethylpyridine; In toluene; at -20 ℃; for 24h; Further stages. Title compound not separated from byproducts.;

DOI:10.1002/anie.200701071

Downstream raw materials:

(R)-α-fluoro-α-phenylacetic acid