(E)-2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylacrylamide

Base Information

Chemical Name:(E)-2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylacrylamide
CAS No.:745051-35-8
Molecular Formula:C₁₈H₂₀N₂O₄S₂
Molecular Weight:392.5
Hs Code.:

Synonyms:(E)-2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylacrylamide

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Chemical Property of (E)-2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylacrylamide

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Technology Process of (E)-2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylacrylamide

There total 2 articles about (E)-2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 96-50-4
2-thiazolylamine

: 745053-01-4
(E)-2-(4-(methylsulfonyl)phenyl)-3-(tetrahydro-2H-pyran-4-yl)acrylic acid

: 745051-35-8
(E)-2-(4-methanesulfonylphenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylacrylamide

Guidance literature:: (E)-2-(4-(methylsulfonyl)phenyl)-3-(tetrahydro-2H-pyran-4-yl)acrylic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; for 0.25h;

2-thiazolylamine; In N,N-dimethyl-formamide; at 20 ℃; for 16h;
DOI:10.1021/jm8003202