Technology Process of beta-D-xylo-Hexopyranosiduronic acid, methyl 3-amino-3,4-dideoxy- (9CI)
There total 11 articles about beta-D-xylo-Hexopyranosiduronic acid, methyl 3-amino-3,4-dideoxy- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
ethanol;
for 192h;
Heating;
DOI:10.1021/jo00255a020
- Guidance literature:
-
Multi-step reaction with 9 steps
1: oxalyl chloride / toluene / 0.5 h
2: Et3N / toluene / 23 °C
3: pentane / 1 h
4: Br(coll)2ClO4 (bromonium bis(collidine) perchlorate) / CH2Cl2 / 1.) 5 min. -78 deg C; 2.) from -78 deg C to RT
5: 290 mg / potassium tert-butoxide / dimethylsulfoxide / 12 h / 23 °C
6: 92 percent / m-chloroperbenzoic acid (mCPBA) / 12 h / 23 °C
7: 99 percent / 4-(N,N-dimethylamino)pyridine, triethylamine / CH2Cl2 / 3 h / 23 °C
8: 76 percent / CAN, silica gel / acetonitrile; H2O / 0.17 h / 23 °C
9: potassium hydroxide / aq. ethanol / 192 h / Heating
With
dmap; potassium hydroxide; oxalyl dichloride; ammonium cerium(IV) nitrate; bromonium bis(collidine) perchlorate; potassium tert-butylate; silica gel; triethylamine; 3-chloro-benzenecarboperoxoic acid;
In
ethanol; dichloromethane; water; dimethyl sulfoxide; toluene; acetonitrile; pentane;
DOI:10.1021/jo00255a020
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 95 percent / 1 h / 150 °C
2: oxalyl chloride / toluene / 0.5 h
3: Et3N / toluene / 23 °C
4: pentane / 1 h
5: Br(coll)2ClO4 (bromonium bis(collidine) perchlorate) / CH2Cl2 / 1.) 5 min. -78 deg C; 2.) from -78 deg C to RT
6: 290 mg / potassium tert-butoxide / dimethylsulfoxide / 12 h / 23 °C
7: 92 percent / m-chloroperbenzoic acid (mCPBA) / 12 h / 23 °C
8: 99 percent / 4-(N,N-dimethylamino)pyridine, triethylamine / CH2Cl2 / 3 h / 23 °C
9: 76 percent / CAN, silica gel / acetonitrile; H2O / 0.17 h / 23 °C
10: potassium hydroxide / aq. ethanol / 192 h / Heating
With
dmap; potassium hydroxide; oxalyl dichloride; ammonium cerium(IV) nitrate; bromonium bis(collidine) perchlorate; potassium tert-butylate; silica gel; triethylamine; 3-chloro-benzenecarboperoxoic acid;
In
ethanol; dichloromethane; water; dimethyl sulfoxide; toluene; acetonitrile; pentane;
DOI:10.1021/jo00255a020
