N-<1,1-dimethyl-2-(4-aminophenyl)ethyl>trifluoroacetamide hydrochloride

Base Information

Chemical Name:N-<1,1-dimethyl-2-(4-aminophenyl)ethyl>trifluoroacetamide hydrochloride
CAS No.:85135-36-0
Molecular Formula:C₁₂H₁₅F₃N₂O*ClH
Molecular Weight:296.72
Hs Code.:

Synonyms:N-<1,1-dimethyl-2-(4-aminophenyl)ethyl>trifluoroacetamide hydrochloride

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Chemical Property of N-<1,1-dimethyl-2-(4-aminophenyl)ethyl>trifluoroacetamide hydrochloride

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Technology Process of N-<1,1-dimethyl-2-(4-aminophenyl)ethyl>trifluoroacetamide hydrochloride

There total 2 articles about N-<1,1-dimethyl-2-(4-aminophenyl)ethyl>trifluoroacetamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 85135-35-9
N-<1,1-dimethyl-2-(4-nitrophenyl)ethyl>trifluoroacetamide

: 85135-36-0
N-<1,1-dimethyl-2-(4-aminophenyl)ethyl>trifluoroacetamide hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; for 1h; under 2740.9 Torr;
DOI:10.1021/jm00360a009

Reference yield:

: 82408-64-8
N-(1,1-dimethyl-2-(4-nitrophenyl)ethyl)amine

: 85135-36-0
N-<1,1-dimethyl-2-(4-aminophenyl)ethyl>trifluoroacetamide hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / tetrahydrofuran / 0.25 h / Ambient temperature

2: 70 percent / conc. HCl, H₂ / 5percent Pd/C / methanol / 1 h / 2740.9 Torr

With hydrogenchloride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1021/jm00360a009