C₄₄H₇₂O₈Si₂

Base Information

• Chemical Name: C₄₄H₇₂O₈Si₂
• CAS No.: 947661-59-8
• Molecular Formula: C₄₄H₇₂O₈Si₂
• Molecular Weight: 785.222
• Mol file: 947661-59-8.mol

Synonyms:C₄₄H₇₂O₈Si₂

Chemical Property of C₄₄H₇₂O₈Si₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₄H₇₂O₈Si₂

There total 21 articles about C₄₄H₇₂O₈Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

C50H86O8Si3 (947661-58-7) → C44H72O8Si2 (947661-59-8)

Guidance literature:

With methanol; camphor-10-sulfonic acid; In dichloromethane; at 0 ℃; for 0.25h;

DOI:10.1016/j.tetlet.2007.05.021

Reference yield:

C13H17O2I (947661-40-7) → C44H72O8Si2 (947661-59-8)

Guidance literature:

Multi-step reaction with 20 steps

1.1: 82 percent / Zn; NaI / methanol / 4 h / Heating

2.1: 85 percent / N-bromosuccinimide / CH₂Cl₂ / 1 h / 0 - 20 °C

3.1: 86 percent / (n-Bu)3SnH; AIBN / benzene / 0.5 h / Heating

4.1: 83 percent / CrO₃; aq. H₂SO₄ / acetone / 1 h / 0 - 20 °C

5.1: 82 percent / triphenylphosphine / tetrahydrofuran / 3 h / Heating

6.1: 80 percent / Li sand / tetrahydrofuran / 2 h / Heating

7.1: 84 percent / imidazole / CH₂Cl₂ / 12 h / 0 - 20 °C

8.1: n-BuLi; BF₃*OEt₂ / tetrahydrofuran / -78 °C

8.2: 88 percent / tetrahydrofuran / -78 °C

9.1: 77 percent / LiAlH₄ / bis-(2-methoxy-ethyl) ether; tetrahydrofuran / 6 h / 155 °C

10.1: 82 percent / CSA / acetone / 1 h / 0 - 20 °C

11.1: 87 percent / Et₃N; DMAP / CH₂Cl₂ / 12 h / 0 - 20 °C

12.1: 79 percent / AD-mix-β; CH3SO2NH2 / 2-methyl-propan-2-ol; H2O / 0 - 20 °C

13.1: 90 percent / 2,6-lutidine / CH₂Cl₂ / 0.5 h / 0 - 20 °C

14.1: 88 percent / methanol; CSA / CH₂Cl₂ / 0.5 h / 0 - 20 °C

15.1: 84 percent / IBX / dimethylsulfoxide; CH₂Cl₂ / 6 h / 0 - 20 °C

16.1: NaNH₂ / diethyl ether / 6 h / 0 - 20 °C

16.2: 84 percent / diethyl ether / 0.33 h / 0 °C

17.1: 92 percent / imidazole / CH₂Cl₂ / 12 h / 0 - 20 °C

18.1: 84 percent / m-CPBA / CH₂Cl₂ / 6 h / 0 - 20 °C

19.1: n-BuLi; BF₃*OEt₃ / tetrahydrofuran / 0.17 h / -78 °C

19.2: 86 percent / tetrahydrofuran / 0.25 h / 0 °C

20.1: 86 percent / methanol; CSA / CH₂Cl₂ / 0.25 h / 0 °C

With 1H-imidazole; 2,6-dimethylpyridine; chromium(VI) oxide; methanol; dmap; N-Bromosuccinimide; lithium aluminium tetrahydride; n-butyllithium; 2,2'-azobis(isobutyronitrile); methanesulfonamide; AD-mix-β; sulfuric acid; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; tri-n-butyl-tin hydride; lithium; sodium amide; triethylamine; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; sodium iodide; zinc; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; camphor-10-sulfonic acid; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; diethylene glycol dimethyl ether; water; dimethyl sulfoxide; acetone; tert-butyl alcohol; benzene; 4.1: Jones' oxidation / 16.2: Wittig reaction;

DOI:10.1016/j.tetlet.2007.05.021

Reference yield:

C16H20O2Cl2 (947661-44-1) → C44H72O8Si2 (947661-59-8)

Guidance literature:

Multi-step reaction with 15 steps

1.1: 80 percent / Li sand / tetrahydrofuran / 2 h / Heating

2.1: 84 percent / imidazole / CH₂Cl₂ / 12 h / 0 - 20 °C

3.1: n-BuLi; BF₃*OEt₂ / tetrahydrofuran / -78 °C

3.2: 88 percent / tetrahydrofuran / -78 °C

4.1: 77 percent / LiAlH₄ / bis-(2-methoxy-ethyl) ether; tetrahydrofuran / 6 h / 155 °C

5.1: 82 percent / CSA / acetone / 1 h / 0 - 20 °C

6.1: 87 percent / Et₃N; DMAP / CH₂Cl₂ / 12 h / 0 - 20 °C

7.1: 79 percent / AD-mix-β; CH3SO2NH2 / 2-methyl-propan-2-ol; H2O / 0 - 20 °C

8.1: 90 percent / 2,6-lutidine / CH₂Cl₂ / 0.5 h / 0 - 20 °C

9.1: 88 percent / methanol; CSA / CH₂Cl₂ / 0.5 h / 0 - 20 °C

10.1: 84 percent / IBX / dimethylsulfoxide; CH₂Cl₂ / 6 h / 0 - 20 °C

11.1: NaNH₂ / diethyl ether / 6 h / 0 - 20 °C

11.2: 84 percent / diethyl ether / 0.33 h / 0 °C

12.1: 92 percent / imidazole / CH₂Cl₂ / 12 h / 0 - 20 °C

13.1: 84 percent / m-CPBA / CH₂Cl₂ / 6 h / 0 - 20 °C

14.1: n-BuLi; BF₃*OEt₃ / tetrahydrofuran / 0.17 h / -78 °C

14.2: 86 percent / tetrahydrofuran / 0.25 h / 0 °C

15.1: 86 percent / methanol; CSA / CH₂Cl₂ / 0.25 h / 0 °C

With 1H-imidazole; 2,6-dimethylpyridine; methanol; dmap; lithium aluminium tetrahydride; n-butyllithium; methanesulfonamide; AD-mix-β; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; lithium; sodium amide; triethylamine; 3-chloro-benzenecarboperoxoic acid; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; camphor-10-sulfonic acid; In tetrahydrofuran; diethyl ether; dichloromethane; diethylene glycol dimethyl ether; water; dimethyl sulfoxide; acetone; tert-butyl alcohol; 11.2: Wittig reaction;

DOI:10.1016/j.tetlet.2007.05.021

upstream raw materials:

C₅₀H₈₆O₈Si₃

C₁₃H₁₇O₂I

C₁₇H₂₅O₃Br

C₁₆H₂₀O₂Cl₂

Downstream raw materials:

C₄₄H₇₄O₈Si₂

C₄₄H₇₀O₈Si₂