1-(4-methoxyphenyl)-4-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-1,4-diazepane

Base Information

Chemical Name:1-(4-methoxyphenyl)-4-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-1,4-diazepane
CAS No.:1243546-03-3
Molecular Formula:C₂₅H₃₄N₂O₂
Molecular Weight:394.557
Hs Code.:

Synonyms:1-(4-methoxyphenyl)-4-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-1,4-diazepane

Suppliers and Price of 1-(4-methoxyphenyl)-4-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-1,4-diazepane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(4-methoxyphenyl)-4-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-1,4-diazepane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(4-methoxyphenyl)-4-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-1,4-diazepane

There total 6 articles about 1-(4-methoxyphenyl)-4-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-1,4-diazepane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1243544-16-2
5-[4-(4-methoxyphenyl)-1,4-diazepan-1-yl]-2,2,4,6,7-pentamethyl-1-benzofuran-3(2H)-one

: 1243546-03-3
1-(4-methoxyphenyl)-4-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-1,4-diazepane

Guidance literature:: With aluminum (III) chloride; lithium aluminium tetrahydride; In tetrahydrofuran; Reflux;
DOI:10.1021/acs.jmedchem.6b00191

Reference yield: 100.0%

: 1243546-03-3
1-(4-methoxyphenyl)-4-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-1,4-diazepane

Guidance literature:

Reference yield:

: 2-methyl-2-(2,3,5-trimethylphenoxy)propanoic acid

: 1243546-03-3
1-(4-methoxyphenyl)-4-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-1,4-diazepane

Guidance literature:: Multi-step reaction with 4 steps

1: polyphosphoric acid / 2 h / 70 °C

2: bromine; acetic acid / 1 h / 20 °C

3: palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate / toluene / Inert atmosphere; Reflux

4: aluminum (III) chloride; lithium aluminium tetrahydride / tetrahydrofuran / Reflux

With aluminum (III) chloride; lithium aluminium tetrahydride; bromine; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; acetic acid; sodium t-butanolate; In tetrahydrofuran; toluene;
DOI:10.1021/acs.jmedchem.6b00191