3-(Chloromethyl)chroman

Base Information

Chemical Name:3-(Chloromethyl)chroman
CAS No.:115822-64-5
Molecular Formula:C₁₀H₁₁ClO
Molecular Weight:182.65
Hs Code.:
DSSTox Substance ID:DTXSID50554028
Mol file:115822-64-5.mol

Synonyms:3-(CHLOROMETHYL)CHROMAN;115822-64-5;3-(chloromethyl)-3,4-dihydro-2H-chromene;3-(Chloromethyl)-3,4-dihydro-2H-1-benzopyran;SCHEMBL20864244;DTXSID50554028;EN300-1967604

Suppliers and Price of 3-(Chloromethyl)chroman

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-(CHLOROMETHYL)CHROMAN 95.00%
5MG
$ 497.33

Total 4 raw suppliers

Chemical Property of 3-(Chloromethyl)chroman

Chemical Property:

PSA：9.23000
LogP:2.47650
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:182.0498427
Heavy Atom Count:12
Complexity:149

Purity/Quality:

98%min ^*data from raw suppliers

3-(CHLOROMETHYL)CHROMAN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(COC2=CC=CC=C21)CCl

Technology Process of 3-(Chloromethyl)chroman

There total 5 articles about 3-(Chloromethyl)chroman which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 76727-28-1
hydroxymethyl-3 chromanne

: 115822-64-5
chloromethyl-3 chromanne

Guidance literature:: With thionyl chloride; In chloroform; for 10h; Ambient temperature;
DOI:10.1016/0223-5234(87)90294-7

Reference yield:

: 57543-66-5
2H-chromene-3-carbonitrile

: 115822-64-5
chloromethyl-3 chromanne

Guidance literature:: Multi-step reaction with 4 steps

1: 94 percent / 10 percent NaOH / 5 h / Heating

2: 90 percent / hydrogen / 10 percent Pd/C / ethanol / 2 h / Ambient temperature

3: 66 percent / LiAlH₄ / diethyl ether / 4 h

4: 88 percent / thionyl chloride / CHCl₃ / 10 h / Ambient temperature

With sodium hydroxide; lithium aluminium tetrahydride; thionyl chloride; hydrogen; palladium on activated charcoal; In diethyl ether; ethanol; chloroform;
DOI:10.1016/0223-5234(87)90294-7

Reference yield:

: 22649-28-1
2H-chromene-3-carboxylic acid

: 115822-64-5
chloromethyl-3 chromanne

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / hydrogen / 10 percent Pd/C / ethanol / 2 h / Ambient temperature

2: 66 percent / LiAlH₄ / diethyl ether / 4 h

3: 88 percent / thionyl chloride / CHCl₃ / 10 h / Ambient temperature

With lithium aluminium tetrahydride; thionyl chloride; hydrogen; palladium on activated charcoal; In diethyl ether; ethanol; chloroform;
DOI:10.1016/0223-5234(87)90294-7