(2R,3S,4R)-1,3,4-tris(4-methoxybenzyloxy)-5-(tert-butyldiphenylsiloxy)-2-pentanethiol

Base Information

Chemical Name:(2R,3S,4R)-1,3,4-tris(4-methoxybenzyloxy)-5-(tert-butyldiphenylsiloxy)-2-pentanethiol
CAS No.:637741-01-6
Molecular Formula:C₄₅H₅₄O₇SSi
Molecular Weight:767.071
Hs Code.:

Synonyms:(2R,3S,4R)-1,3,4-tris(4-methoxybenzyloxy)-5-(tert-butyldiphenylsiloxy)-2-pentanethiol

Suppliers and Price of (2R,3S,4R)-1,3,4-tris(4-methoxybenzyloxy)-5-(tert-butyldiphenylsiloxy)-2-pentanethiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3S,4R)-1,3,4-tris(4-methoxybenzyloxy)-5-(tert-butyldiphenylsiloxy)-2-pentanethiol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3S,4R)-1,3,4-tris(4-methoxybenzyloxy)-5-(tert-butyldiphenylsiloxy)-2-pentanethiol

There total 7 articles about (2R,3S,4R)-1,3,4-tris(4-methoxybenzyloxy)-5-(tert-butyldiphenylsiloxy)-2-pentanethiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 637741-59-4
thioacetic acid S-[4-(tert-butyl-diphenyl-silanyloxy)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-butyl] ester

: 637741-01-6
(2R,3S,4R)-1,3,4-tris(4-methoxybenzyloxy)-5-(tert-butyldiphenylsiloxy)-2-pentanethiol

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃; for 2h;
DOI:10.1039/b305818b

Reference yield:

: 4-Nitro-benzoic acid (1S,2S,3R)-4-(tert-butyl-diphenyl-silanyloxy)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-butyl ester

: 637741-01-6
(2R,3S,4R)-1,3,4-tris(4-methoxybenzyloxy)-5-(tert-butyldiphenylsiloxy)-2-pentanethiol

Guidance literature:: Multi-step reaction with 4 steps

1: 2.67 g / diisobutylaluminum hydride / CH₂Cl₂; hexane / 4 h / -78 °C

2: triethylamine / CH₂Cl₂ / 1 h / 0 °C

3: 56 percent / toluene; dimethylformamide / 11 h / Heating

4: 88 percent / lithium aluminum hydride / diethyl ether / 2 h / 0 °C

With lithium aluminium tetrahydride; diisobutylaluminium hydride; triethylamine; In diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1039/b305818b

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 637741-01-6
(2R,3S,4R)-1,3,4-tris(4-methoxybenzyloxy)-5-(tert-butyldiphenylsiloxy)-2-pentanethiol

Guidance literature:: Multi-step reaction with 6 steps

1: 81 percent / imidazole / dimethylformamide / 3 h / 20 °C

2: diisopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 4 h / 20 °C

3: 2.67 g / diisobutylaluminum hydride / CH₂Cl₂; hexane / 4 h / -78 °C

4: triethylamine / CH₂Cl₂ / 1 h / 0 °C

5: 56 percent / toluene; dimethylformamide / 11 h / Heating

6: 88 percent / lithium aluminum hydride / diethyl ether / 2 h / 0 °C

With 1H-imidazole; lithium aluminium tetrahydride; di-isopropyl azodicarboxylate; diisobutylaluminium hydride; triethylamine; triphenylphosphine; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide; toluene; 2: Mitsunobu reaction;
DOI:10.1039/b305818b