1-(2,4-Difluorophenyl)piperazine dihydrochloride

Base Information

Chemical Name:1-(2,4-Difluorophenyl)piperazine dihydrochloride
CAS No.:115761-77-8
Molecular Formula:C₁₀H₁₂F₂N₂*ClH
Molecular Weight:234.676
Hs Code.:2933599090
DSSTox Substance ID:DTXSID00556299
Mol file:115761-77-8.mol

Synonyms:115761-77-8;1-(2,4-DIFLUOROPHENYL)PIPERAZINE DIHYDROCHLORIDE;1-(2,4-difluorophenyl)piperazine;dihydrochloride;1-(2,4-Difluoro-phenyl)-piperazine dihydrochloride;SCHEMBL5987897;DTXSID00556299;XJXLAHNBVVIBFD-UHFFFAOYSA-N;AKOS022180170;1-(2,4-DIFLUOROPHENYL)PIPERAZINEDIHYDROCHLORIDE;1-(2,4-Difluorophenyl)piperazine--hydrogen chloride (1/2)

Suppliers and Price of 1-(2,4-Difluorophenyl)piperazine dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 1-(2,4-Difluorophenyl)piperazine dihydrochloride

Chemical Property:

Vapor Pressure:1.83E-05mmHg at 25°C
Boiling Point:358°C at 760 mmHg
Flash Point:170.3°C
PSA：15.27000
LogP:3.37220
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:270.0502102
Heavy Atom Count:16
Complexity:183

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C2=C(C=C(C=C2)F)F.Cl.Cl

Technology Process of 1-(2,4-Difluorophenyl)piperazine dihydrochloride

There total 2 articles about 1-(2,4-Difluorophenyl)piperazine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 348-57-2
2,4-difluorobromobenzene

: 115761-77-8
1-(2,4-difluorophenyl)piperazine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: XPhos; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium t-butanolate / toluene / 16 h / 110 °C

2: hydrogenchloride / 1,4-dioxane / 0.5 h / 15 °C

With hydrogenchloride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium t-butanolate; XPhos; In 1,4-dioxane; toluene;