1-phenyl-2-(N-methylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone

Base Information

Chemical Name:1-phenyl-2-(N-methylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone
CAS No.:133387-97-0
Molecular Formula:C₂₂H₂₅N₃O₂
Molecular Weight:363.459
Hs Code.:

Synonyms:1-phenyl-2-(N-methylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-phenyl-2-(N-methylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone

Chemical Property:

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Technology Process of 1-phenyl-2-(N-methylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone

There total 2 articles about 1-phenyl-2-(N-methylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.6%

: 109-01-3
1-methyl-piperazine

: 133387-96-9
1-phenyl-2-chloroacetyl-1,4-dihydro-3(2H)-isoquinolinone

: 133387-97-0
1-phenyl-2-(N-methylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone

Guidance literature:: With sodium carbonate; potassium iodide; In N,N-dimethyl-formamide; for 2h; Ambient temperature;

Reference yield:

: 17507-05-0
1-phenyl-1,4-dihydro-3(2H)-isoquinolinone

: 133387-97-0
1-phenyl-2-(N-methylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone

Guidance literature:: Multi-step reaction with 2 steps

1: 92.5 percent / benzene / 2 h / Heating

2: 40.6 percent / Na₂CO₃, KI / dimethylformamide / 2 h / Ambient temperature

With sodium carbonate; potassium iodide; In N,N-dimethyl-formamide; benzene;