tert-butyl[4-(2-(bis-carboxymethyl-amino)-3-{4-[4-(3,7,12-trihydroxy-10,13-dimethylhexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoylamino]-phenyl}-propyl)-7-carboxymethyl-[1,4,7]triazonan-1-yl]-acetic acid

Base Information

• Chemical Name: tert-butyl[4-(2-(bis-carboxymethyl-amino)-3-{4-[4-(3,7,12-trihydroxy-10,13-dimethylhexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoylamino]-phenyl}-propyl)-7-carboxymethyl-[1,4,7]triazonan-1-yl]-acetic acid
• CAS No.: 1173056-08-0
• Molecular Formula: C₆₃H₁₀₅N₅O₁₂
• Molecular Weight: 1124.55
• Mol file: 1173056-08-0.mol

Synonyms:tert-butyl[4-(2-(bis-carboxymethyl-amino)-3-{4-[4-(3,7,12-trihydroxy-10,13-dimethylhexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoylamino]-phenyl}-propyl)-7-carboxymethyl-[1,4,7]triazonan-1-yl]-acetic acid

Chemical Property of tert-butyl[4-(2-(bis-carboxymethyl-amino)-3-{4-[4-(3,7,12-trihydroxy-10,13-dimethylhexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoylamino]-phenyl}-propyl)-7-carboxymethyl-[1,4,7]triazonan-1-yl]-acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl[4-(2-(bis-carboxymethyl-amino)-3-{4-[4-(3,7,12-trihydroxy-10,13-dimethylhexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoylamino]-phenyl}-propyl)-7-carboxymethyl-[1,4,7]triazonan-1-yl]-acetic acid

There total 1 articles about tert-butyl[4-(2-(bis-carboxymethyl-amino)-3-{4-[4-(3,7,12-trihydroxy-10,13-dimethylhexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoylamino]-phenyl}-propyl)-7-carboxymethyl-[1,4,7]triazonan-1-yl]-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

(R)-3-[4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoyl]-thiazolidin-2-one (1029127-60-3) + C39H67N5O8 (1041634-48-3) → tert-butyl[4-(2-(bis-carboxymethyl-amino)-3-{4-[4-(3,7,12-trihydroxy-10,13-dimethylhexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoylamino]-phenyl}-propyl)-7-carboxymethyl-[1,4,7]triazonan-1-yl]-acetic acid (1173056-08-0)

Guidance literature:

With triethylamine; In dichloromethane; for 72h; Reflux;

DOI:10.1039/b823000e

Reference yield: 90.0%

tert-butyl[4-(2-(bis-carboxymethyl-amino)-3-{4-[4-(3,7,12-trihydroxy-10,13-dimethylhexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoylamino]-phenyl}-propyl)-7-carboxymethyl-[1,4,7]triazonan-1-yl]-acetic acid (1173056-08-0) → [4-(2-(bis-carboxymethyl-amino)-3-{4-[4-(3,7,12-trihydroxy-10,13-dimethyl-hexadecahydrocyclopenta[a]phenanthren-17-yl)-pentanoylamino]-phenyl}-propyl)-7-carboxymethyl-[1,4,7]triazonan-1-yl]-acetic acid (1173056-16-0)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 0 - 20 ℃;

DOI:10.1039/b823000e

upstream raw materials:

(R)-3-[4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoyl]-thiazolidin-2-one

C₃₉H₆₇N₅O₈

Downstream raw materials:

[4-(2-(bis-carboxymethyl-amino)-3-{4-[4-(3,7,12-trihydroxy-10,13-dimethyl-hexadecahydrocyclopenta[a]phenanthren-17-yl)-pentanoylamino]-phenyl}-propyl)-7-carboxymethyl-[1,4,7]triazonan-1-yl]-acetic acid