5,8-dimethoxy-2,3-bis(phenylthio)-1,4-dihydro-1,4-methanonaphthalene

Base Information

• Chemical Name: 5,8-dimethoxy-2,3-bis(phenylthio)-1,4-dihydro-1,4-methanonaphthalene
• CAS No.: 507235-26-9
• Molecular Formula: C₂₅H₂₂O₂S₂
• Molecular Weight: 418.58
• Mol file: 507235-26-9.mol

Synonyms:5,8-dimethoxy-2,3-bis(phenylthio)-1,4-dihydro-1,4-methanonaphthalene

Chemical Property of 5,8-dimethoxy-2,3-bis(phenylthio)-1,4-dihydro-1,4-methanonaphthalene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,8-dimethoxy-2,3-bis(phenylthio)-1,4-dihydro-1,4-methanonaphthalene

There total 2 articles about 5,8-dimethoxy-2,3-bis(phenylthio)-1,4-dihydro-1,4-methanonaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

thiophenol (108-98-5) + 2,3-dibromo-5,8-dimethoxy-1,4-dihydro-1,4-methanonaphthalene (507235-20-3) → 5,8-dimethoxy-2,3-bis(phenylthio)-1,4-dihydro-1,4-methanonaphthalene (507235-26-9)

Guidance literature:

With potassium hydroxide; In N,N-dimethyl-formamide; at 80 ℃; for 24h;

DOI:10.1002/1099-0690(200212)2002:23<4024::AID-EJOC4024>3.0.CO;2-N

Reference yield:

2-bromo-1,4-dihydro-1,4-methano-5,8-dimethoxynaphthalene (286414-10-6) → 5,8-dimethoxy-2,3-bis(phenylthio)-1,4-dihydro-1,4-methanonaphthalene (507235-26-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 100 percent / Br₂ / CCl₄ / Heating

2: 50 percent / tBuOK / tetrahydrofuran / 6 h / Heating

3: 68 percent / KOH / dimethylformamide / 24 h / 80 °C

With potassium hydroxide; potassium tert-butylate; bromine; In tetrahydrofuran; tetrachloromethane; N,N-dimethyl-formamide;

DOI:10.1002/1099-0690(200212)2002:23<4024::AID-EJOC4024>3.0.CO;2-N

Reference yield: 66.0%

5,8-dimethoxy-2,3-bis(phenylthio)-1,4-dihydro-1,4-methanonaphthalene (507235-26-9) → 5,8-dimethoxy-2,3-bis(phenylsulfonyl)-1,4-dihydro-1,4-methanonaphthalene

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; water; at 0 ℃; for 6h;

DOI:10.1002/1099-0690(200212)2002:23<4024::AID-EJOC4024>3.0.CO;2-N

upstream raw materials:

thiophenol

2,3-dibromo-5,8-dimethoxy-1,4-dihydro-1,4-methanonaphthalene

2-bromo-1,4-dihydro-1,4-methano-5,8-dimethoxynaphthalene