3-(Trifluoromethyl)pyrido[2,3-b]pyrazine

Base Information

Chemical Name:3-(Trifluoromethyl)pyrido[2,3-b]pyrazine
CAS No.:115652-64-7
Molecular Formula:C₈H₄F₃N₃
Molecular Weight:199.135
Hs Code.:
DSSTox Substance ID:DTXSID50557256
Wikidata:Q82439109
Mol file:115652-64-7.mol

Synonyms:3-(Trifluoromethyl)pyrido[2,3-b]pyrazine;115652-64-7;Pyrido[2,3-b]pyrazine, 3-(trifluoromethyl)- (9CI);DTXSID50557256;Pyrido[2,3-b]pyrazine,3-(trifluoromethyl)-(9ci)

Suppliers and Price of 3-(Trifluoromethyl)pyrido[2,3-b]pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-(Trifluoromethyl)pyrido[2,3-b]pyrazine

Chemical Property:

Melting Point:121.5-123 °C
Boiling Point:238.1±35.0 °C(Predicted)
PKA:-0.65±0.30(Predicted)
PSA：38.67000
Density:1.456±0.06 g/cm3(Predicted)
LogP:2.04360
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:0
Exact Mass:199.03573163
Heavy Atom Count:14
Complexity:207

Purity/Quality:: 99%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=NC=C(N=C2N=C1)C(F)(F)F

Technology Process of 3-(Trifluoromethyl)pyrido[2,3-b]pyrazine

There total 1 articles about 3-(Trifluoromethyl)pyrido[2,3-b]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 452-58-4
2,3-Diaminopyridine

: 431-67-4
1,1-dibromo-3,3,3-trifluoroacetone

: 115652-64-7
3-(trifluoromethyl)pyrido<2,3-b>pyrazine

: 115652-65-8
2-(trifluoromethyl)pyrido<2,3-b>pyrazine

Guidance literature:: With sodium acetate; Yield given. Multistep reaction. Yields of byproduct given; 1.) 98 deg C, 30 min, 2.) MeOH, RT, 3 h;
DOI:10.1021/jo00256a034