Technology Process of 3-(methylamino)-4-aminoacetophenone
There total 6 articles about 3-(methylamino)-4-aminoacetophenone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: nitric acid, acetic anhydride
2: KOH / ethanol; H2O
3: 98 percent / trifluoroacetic anhydride / 0.42 h
4: 1.) K2CO3 / 1.) dimethoxyethane; 2.) r.t., overnight
5: hydrogen / 10percent palladium on charcoal / ethanol / 1 h
With
potassium hydroxide; hydrogen; nitric acid; acetic anhydride; potassium carbonate; trifluoroacetic anhydride;
palladium on activated charcoal;
In
ethanol; water;
DOI:10.1021/ja00334a053
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
ethanol;
for 4h;
Ambient temperature;
DOI:10.1021/ja00410a040
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 98 percent / trifluoroacetic anhydride / 0.42 h
2: 1.) K2CO3 / 1.) dimethoxyethane; 2.) r.t., overnight
3: hydrogen / 10percent palladium on charcoal / ethanol / 1 h
With
hydrogen; potassium carbonate; trifluoroacetic anhydride;
palladium on activated charcoal;
In
ethanol;
DOI:10.1021/ja00334a053
