DG-ME PHOSPHONAMIDITE

Base Information

Chemical Name:DG-ME PHOSPHONAMIDITE
CAS No.:115131-08-3
Molecular Formula:C42H53 N6 O7 P
Molecular Weight:784.88
Hs Code.:

Synonyms:DG-ME PHOSPHONAMIDITE

Suppliers and Price of DG-ME PHOSPHONAMIDITE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of DG-ME PHOSPHONAMIDITE

Chemical Property:

PKA:9.16±0.20(Predicted)
PSA：155.65000
LogP:7.54620

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of DG-ME PHOSPHONAMIDITE

There total 2 articles about DG-ME PHOSPHONAMIDITE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 51747-24-1
N,N-diisopropylamino methylphosphonamidic chloride

: 68892-41-1
5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine

: 115131-08-3
C₄₂H₅₃N₆O₇P

Guidance literature:: N,N-diisopropylamino methylphosphonamidic chloride; With N-ethyl-N,N-diisopropylamine; In dichloromethane; toluene; for 0.0833333h;

5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine; With 5,6,9,10-tetrahydro-4H,8H-pyrido[3,2,1-ij][1,6]naphthyridine; In dichloromethane; toluene; for 0.166667h;

Reference yield: 90.0%

: 68892-41-1
5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine

: 115131-08-3
C₄₂H₅₃N₆O₇P

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 0.333333h; Ambient temperature;
DOI:10.1016/S0040-4039(00)95529-1

Reference yield:

: 115131-08-3
C₄₂H₅₃N₆O₇P

: [(2R,3S,5R)-5-(6-Benzylamino-purin-9-yl)-3-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-yl]-methanol

: C₆₉H₇₅N₁₀O₁₁PSi

: C₆₉H₇₅N₁₀O₁₁PSi

Guidance literature:: With 5-<(1R,2R)-2-(2-methoxy)bornyl>tetrazole; In dichloromethane; for 2h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; further reagents;
DOI:10.1080/07328319708002948