(3aR,4R,5R,6aS)-4-((E)-4,4-difluoro-3-oxo-1-octenyl)-2-oxo-5-(phenylmethoxy)-hexahydro-2H-cyclopenta[b]furan

Base Information

Chemical Name:(3aR,4R,5R,6aS)-4-((E)-4,4-difluoro-3-oxo-1-octenyl)-2-oxo-5-(phenylmethoxy)-hexahydro-2H-cyclopenta[b]furan
CAS No.:1236109-26-4
Molecular Formula:C₂₂H₂₆F₂O₄
Molecular Weight:392.443
Hs Code.:

Synonyms:(3aR,4R,5R,6aS)-4-((E)-4,4-difluoro-3-oxo-1-octenyl)-2-oxo-5-(phenylmethoxy)-hexahydro-2H-cyclopenta[b]furan

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Chemical Property of (3aR,4R,5R,6aS)-4-((E)-4,4-difluoro-3-oxo-1-octenyl)-2-oxo-5-(phenylmethoxy)-hexahydro-2H-cyclopenta[b]furan

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Technology Process of (3aR,4R,5R,6aS)-4-((E)-4,4-difluoro-3-oxo-1-octenyl)-2-oxo-5-(phenylmethoxy)-hexahydro-2H-cyclopenta[b]furan

There total 1 articles about (3aR,4R,5R,6aS)-4-((E)-4,4-difluoro-3-oxo-1-octenyl)-2-oxo-5-(phenylmethoxy)-hexahydro-2H-cyclopenta[b]furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 163074-98-4
[(3aR,4R,5R,6aS)-hexahydro-2-oxo-5-(phenylmethoxy)-2H-cyclopenta[b]furan-4-carboxaldehyde]

: 50889-46-8
dimethyl (3,3-difluoro-2-oxoheptyl)-phosphonate

: 1236109-26-4
(3aR,4R,5R,6aS)-4-((E)-4,4-difluoro-3-oxo-1-octenyl)-2-oxo-5-(phenylmethoxy)-hexahydro-2H-cyclopenta[b]furan

Guidance literature:: dimethyl (3,3-difluoro-2-oxoheptyl)-phosphonate; With zinc(II) hydroxide; In tert-butyl methyl ether; water; for 1h; Inert atmosphere;

[(3aR,4R,5R,6aS)-hexahydro-2-oxo-5-(phenylmethoxy)-2H-cyclopenta[b]furan-4-carboxaldehyde]; In dichloromethane; tert-butyl methyl ether; water; for 24h; Product distribution / selectivity;