C₂₁H₂₈N₂O₃

Base Information

• Chemical Name: C₂₁H₂₈N₂O₃
• CAS No.: 1575790-50-9
• Molecular Formula: C₂₁H₂₈N₂O₃
• Molecular Weight: 356.465
• Mol file: 1575790-50-9.mol

Synonyms:C₂₁H₂₈N₂O₃

Chemical Property of C₂₁H₂₈N₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₂₈N₂O₃

There total 1 articles about C₂₁H₂₈N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(E)-4-hydroxy-4′-methoxyazobenzene (103939-79-3) + 8-bromooctanol (50816-19-8) → C21H28N2O3 (1575790-50-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 14h; Inert atmosphere;

DOI:10.1021/ja5041573

Reference yield: 86.0%

C21H28N2O3 (1575790-50-9) → C21H27BrN2O2 (149474-78-2)

Guidance literature:

With phosphorus tribromide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

DOI:10.1021/ja5041573

Reference yield:

C21H28N2O3 (1575790-50-9) → C71H86N6O11 (1616282-97-3)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphorus tribromide / N,N-dimethyl-formamide; dichloromethane; tetrahydrofuran / 20 °C / Inert atmosphere

2: potassium carbonate / N,N-dimethyl-formamide / 12 h / 70 °C / Inert atmosphere

With phosphorus tribromide; potassium carbonate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja5041573

upstream raw materials:

(E)-4-hydroxy-4′-methoxyazobenzene

8-bromooctanol

Downstream raw materials:

C₇₁H₈₆N₆O₁₁

C₇₀H₈₆N₆O₁₀

C₇₀H₈₅ClN₆O₉

C₇₄H₉₁N₈O₉⁽¹⁺⁾*Cl^(1-)

Refernces