4-(2-Chloroacetyl)-N,N-dimethyl-1H-pyrrole-2-carboxamide

Base Information

Chemical Name:4-(2-Chloroacetyl)-N,N-dimethyl-1H-pyrrole-2-carboxamide
CAS No.:115027-25-3
Molecular Formula:C₉H₁₁ClN₂O₂
Molecular Weight:214.652
Hs Code.:
DSSTox Substance ID:DTXSID50577555
Wikidata:Q82467592
Mol file:115027-25-3.mol

Synonyms:115027-25-3;4-(2-Chloroacetyl)-N,N-dimethyl-1H-pyrrole-2-carboxamide;1H-Pyrrole-2-carboxamide, 4-(chloroacetyl)-N,N-dimethyl- (9CI);SCHEMBL9792751;DTXSID50577555;4-(Chloroacetyl)-N,N-dimethyl-1H-pyrrole-2-carboxamide

Suppliers and Price of 4-(2-Chloroacetyl)-N,N-dimethyl-1H-pyrrole-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-(2-Chloroacetyl)-N,N-dimethyl-1H-pyrrole-2-carboxamide

Chemical Property:

Boiling Point:447.2±35.0 °C(Predicted)
PKA:13.80±0.50(Predicted)
PSA：53.17000
Density:1.293±0.06 g/cm3(Predicted)
LogP:1.13800
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:214.0509053
Heavy Atom Count:14
Complexity:243

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(=O)C1=CC(=CN1)C(=O)CCl

Technology Process of 4-(2-Chloroacetyl)-N,N-dimethyl-1H-pyrrole-2-carboxamide

There total 1 articles about 4-(2-Chloroacetyl)-N,N-dimethyl-1H-pyrrole-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 115027-25-3
1-(2-N,N-dimethylaminocarbonylpyrrol-4-yl)-2-chloroethanone

Guidance literature:

Reference yield:

: 115027-25-3
1-(2-N,N-dimethylaminocarbonylpyrrol-4-yl)-2-chloroethanone

: 2114-02-5
amidinothiocarbamide

: 115027-58-2
N-[4-(2-N,N-Dimethylaminocarbonylpyrrol-4-yl)-thiazol-2-yl]guanidine acetate

Guidance literature:: With sodium iodide; In methanol; sodium hydrogencarbonate; acetic acid; acetone;

Reference yield:

: 115027-25-3
1-(2-N,N-dimethylaminocarbonylpyrrol-4-yl)-2-chloroethanone

: 123310-57-6
N-[4-(2-N,N-Dimethylaminomethylpyrrol-4-yl)thiazol-2-yl]guanidine acetate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium iodide / methanol; sodium hydrogencarbonate; acetic acid; acetone

2: hydrogenchloride; sodium hydroxide; borane / tetrahydrofuran; acetic acid

With hydrogenchloride; sodium hydroxide; sodium iodide; borane; In tetrahydrofuran; methanol; sodium hydrogencarbonate; acetic acid; acetone;