4-[2-(6-Methyl-2-pyridyl)ethoxy]nitrobenzene

Base Information

Chemical Name:4-[2-(6-Methyl-2-pyridyl)ethoxy]nitrobenzene
CAS No.:85002-84-2
Molecular Formula:C₁₄H₁₄N₂O₃
Molecular Weight:258.277
Hs Code.:
DSSTox Substance ID:DTXSID501258530

Synonyms:4-[2-(6-methyl-2-pyridyl)ethoxy]nitrobenzene;SCHEMBL11087448;YZHZNFQXYLNLMJ-UHFFFAOYSA-N;DTXSID501258530;85002-84-2;2-methyl-6-[2-(4-nitrophenoxy)ethyl]pyridine

Suppliers and Price of 4-[2-(6-Methyl-2-pyridyl)ethoxy]nitrobenzene

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[2-(6-Methyl-2-pyridyl)ethoxy]nitrobenzene

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:258.10044231
Heavy Atom Count:19
Complexity:285

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=NC(=CC=C1)CCOC2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 4-[2-(6-Methyl-2-pyridyl)ethoxy]nitrobenzene

There total 1 articles about 4-[2-(6-Methyl-2-pyridyl)ethoxy]nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.9%

: 934-78-1
2-(6-methylpyridin-2-yl)-ethanol

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 85002-84-2
4-[2-(6-methyl-pyridin-2-yl)ethoxy]nitrobenzene

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 1h;
DOI:10.1248/cpb.30.3580

Reference yield:

: 85002-84-2
4-[2-(6-methyl-pyridin-2-yl)ethoxy]nitrobenzene

: 85583-36-4
4-[2-(6-methyl-pyridin-2-yl)ethoxy]aniline

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 760 Torr; Ambient temperature;

Reference yield:

: 85002-84-2
4-[2-(6-methyl-pyridin-2-yl)ethoxy]nitrobenzene

: 74773-19-6
5-{4-[2-(6-methyl-pyridin-2-yl)ethoxy]benzyl}-2,4-thiazolidinedione

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen / 10percent Pd-C / methanol / 760 Torr / Ambient temperature

2: 1.) NaNO₂, conc. HCl, 2.) Cu₂O / 1.) acetone, water, 5 deg C, 30 min, 2.) acetone, water, 35 deg C

3: 2.) 2N HCl / 1.) sulfolane, 120 deg C, 10 h; 2.) sulfolane, 100 deg C, 8 h

With copper(I) oxide; hydrogenchloride; hydrogen; sodium nitrite; palladium on activated charcoal; In methanol;
DOI:10.1248/cpb.30.3580