Cyclopentanesulfonic acid, 2-amino-, cis- (9CI)

Base Information

• Chemical Name: Cyclopentanesulfonic acid, 2-amino-, cis- (9CI)
• CAS No.: 114850-07-6
• Molecular Formula: C₅H₁₁NO₃S
• Molecular Weight: 165.213
• Mol file: 114850-07-6.mol

Synonyms:Cyclopentanesulfonicacid, 2-amino-, cis- (9CI); Cyclopentanesulfonic acid, 2-amino-, cis-(?à)-; (?à)-cis-2-Aminocyclopentanesulfonic acid

Chemical Property of Cyclopentanesulfonic acid, 2-amino-, cis- (9CI)

Chemical Property:

• Melting Point: 272 °C (decomp)
• PKA: 1.22±0.20(Predicted)
• Density: 1.43±0.1 g/cm3(Predicted)

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclopentanesulfonic acid, 2-amino-, cis- (9CI)

There total 10 articles about Cyclopentanesulfonic acid, 2-amino-, cis- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3,3a,4,5,6,6a-hexahydro-2H-cyclopentathiazole-2-thione (1437-97-4,89711-92-2) → cis-(+/-)-2-aminocyclopentane-1-sulfonic acid (110578-84-2,114850-07-6)

Guidance literature:

With formic acid; dihydrogen peroxide; In water; at 0 - 5 ℃;

DOI:10.1002/ejoc.200900759

Reference yield: 37.0%

3-(((benzyloxy)carbonyl)amino)cyclopentane-1-sulfonic acid → 3-aminocyclopentane-4-sulfonic acid (110578-84-2,114850-07-6)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; water; at 20 ℃; for 16h;

Reference yield:

(+/-)-trans-2-azidocyclopentanesulfonic acid → (+/-)-trans-2-aminocyclopentanesulfonic acid (110578-84-2,114850-07-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 72h; under 760 Torr;

upstream raw materials:

6-azabicyclo<3.1.0>hexane

cyclopentene

3,3a,4,5,6,6a-hexahydro-2H-cyclopentathiazole-2-thione

Refernces

• 1、 Chen, Ning,Jia, Weiyi,Xu, Jiaxi. "A versatile synthesis of various substituted taurines from vicinal amino alcohols and aziridines". experimental part. p. 5841 - 5846. Retrieved 2010/03/03.
• 2、 Mittendorf, Joachim,Kunisch, Franz,Matzke, Michael,Militzer, Hans-Christian,Schmidt, Axel,Schoenfeld, Wolfgang. "Novel antifungal β-amino acids: Synthesis and activity against Candida albicans". . p. 433 - 436. Retrieved 2007/10/03.