(E)-N-(4-methoxybenzyloxy)-3-(1-(2-phenoxyethyl)-1H-1,2,3-triazol-4-yl)acrylamide

Base Information

• Chemical Name: (E)-N-(4-methoxybenzyloxy)-3-(1-(2-phenoxyethyl)-1H-1,2,3-triazol-4-yl)acrylamide
• CAS No.: 1092115-78-0
• Molecular Formula: C₂₁H₂₂N₄O₄
• Molecular Weight: 394.43
• Mol file: 1092115-78-0.mol

Synonyms:(E)-N-(4-methoxybenzyloxy)-3-(1-(2-phenoxyethyl)-1H-1,2,3-triazol-4-yl)acrylamide

Chemical Property of (E)-N-(4-methoxybenzyloxy)-3-(1-(2-phenoxyethyl)-1H-1,2,3-triazol-4-yl)acrylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-N-(4-methoxybenzyloxy)-3-(1-(2-phenoxyethyl)-1H-1,2,3-triazol-4-yl)acrylamide

There total 1 articles about (E)-N-(4-methoxybenzyloxy)-3-(1-(2-phenoxyethyl)-1H-1,2,3-triazol-4-yl)acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H13NO3 (1312592-14-5) + 1-azido-2-phenoxyethane (70659-90-4) → (E)-N-(4-methoxybenzyloxy)-3-(1-(2-phenoxyethyl)-1H-1,2,3-triazol-4-yl)acrylamide (1092115-78-0)

Guidance literature:

With triethylphosphite copper(I) iodide complex; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/jm8005355

Reference yield: 61.0%

(E)-N-(4-methoxybenzyloxy)-3-(1-(2-phenoxyethyl)-1H-1,2,3-triazol-4-yl)acrylamide (1092115-78-0) → (E)-N-hydroxy-3-(1-(2-phenoxyethyl)-1H-1,2,3-triazol-4-yl)acrylamide (1092115-53-1)

Guidance literature:

With chlorotriisopropylsilane; trifluoroacetic acid; In dichloromethane; at 20 ℃;

DOI:10.1021/jm8005355

upstream raw materials:

C₁₃H₁₃NO₃

1-azido-2-phenoxyethane

Downstream raw materials:

(E)-N-hydroxy-3-(1-(2-phenoxyethyl)-1H-1,2,3-triazol-4-yl)acrylamide