(1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide

Base Information

Chemical Name:(1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide
CAS No.:945551-93-9
Molecular Formula:C₂₅H₃₂N₂O₄
Molecular Weight:424.54
Hs Code.:

Synonyms:(1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide

Suppliers and Price of (1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide

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Technology Process of (1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide

There total 1 articles about (1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 3182-95-4
L-Phenylalaninol

: 119908-76-8
cis-3,3-dimethylcyclopropane-1,2-dicarbonyl dichloride

: 945551-93-9
(1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide

Guidance literature:: With triethylamine; In chloroform; at 0 - 20 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.tetasy.2012.06.014

Reference yield: 39.0%

: 945551-93-9
(1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide

: 945551-89-3
(1R,2S)-1,2-bis[4(S)-benzyloxazolin-2-yl]-3,3-dimethylcyclopropane

Guidance literature:: With dmap; triethylamine; p-toluenesulfonyl chloride; In dichloromethane; at 20 ℃; for 27h; Inert atmosphere;
DOI:10.1016/j.tetasy.2012.06.014