(S)-methyl 1-((R)-(benzyloxycarbonylamino)(phenyl)methyl)-2-oxocyclohexanecarboxylate

Base Information

• Chemical Name: (S)-methyl 1-((R)-(benzyloxycarbonylamino)(phenyl)methyl)-2-oxocyclohexanecarboxylate
• CAS No.: 1203706-60-8
• Molecular Formula: C₂₃H₂₅NO₅
• Molecular Weight: 395.455
• Mol file: 1203706-60-8.mol

Synonyms:(S)-methyl 1-((R)-(benzyloxycarbonylamino)(phenyl)methyl)-2-oxocyclohexanecarboxylate

Chemical Property of (S)-methyl 1-((R)-(benzyloxycarbonylamino)(phenyl)methyl)-2-oxocyclohexanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of (S)-methyl 1-((R)-(benzyloxycarbonylamino)(phenyl)methyl)-2-oxocyclohexanecarboxylate

There total 1 articles about (S)-methyl 1-((R)-(benzyloxycarbonylamino)(phenyl)methyl)-2-oxocyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(methoxycarbonyl)cyclohexanone (41302-34-5) + benzyl N-benzylidenecarbamate (172794-72-8) → (S)-methyl 1-((R)-(benzyloxycarbonylamino)(phenyl)methyl)-2-oxocyclohexanecarboxylate (1203706-60-8) + (R)-methyl 1-((S)-(benzyloxycarbonylamino)(phenyl)methyl)-2-oxocyclohexanecarboxylate

Guidance literature:

With n-butyllithium; (R)-3,3′-bis(3,4,5-trifluorophenyl)[1,1′-binaphthalene]-2,2′-diol; tert-butyl alcohol; In hexane; toluene; at -78 ℃; for 2h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1021/ja909874b

upstream raw materials:

2-(methoxycarbonyl)cyclohexanone

benzyl N-benzylidenecarbamate