N-hydroxy-1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carboxamidine

Base Information

Chemical Name:N-hydroxy-1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carboxamidine
CAS No.:849663-47-4
Molecular Formula:C₁₆H₁₆N₆O₂
Molecular Weight:324.342
Hs Code.:

<i>N</i>-hydroxy-1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-<i>as</i>-indacene-3-carboxamidine

Synonyms:N-hydroxy-1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carboxamidine

Suppliers and Price of N-hydroxy-1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carboxamidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-hydroxy-1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carboxamidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-hydroxy-1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carboxamidine

There total 3 articles about N-hydroxy-1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 849663-46-3
1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carbonitrile

: 849663-47-4
N-hydroxy-1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carboxamidine

Guidance literature:: With hydroxylamine hydrochloride; potassium carbonate; In ethanol; for 4h; Heating;
DOI:10.1016/j.bmcl.2005.01.023

Reference yield:

: 586353-52-8
1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carboxylic acid amide

: 849663-47-4
N-hydroxy-1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carboxamidine

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / TFAA; pyridine / 0.5 h / 20 °C

2: 76 percent / NH₂OH*HCl; K₂CO₃ / ethanol / 4 h / Heating

With pyridine; hydroxylamine hydrochloride; potassium carbonate; trifluoroacetic anhydride; In ethanol;
DOI:10.1016/j.bmcl.2005.01.023

Reference yield:

: 586353-03-9
1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carboxylic acid ethyl ester

: 849663-47-4
N-hydroxy-1-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-1,2,6,7-tetraaza-as-indacene-3-carboxamidine

Guidance literature:: Multi-step reaction with 3 steps

1: aq. NH₃ / methanol / 25 - 60 °C

2: 85 percent / TFAA; pyridine / 0.5 h / 20 °C

3: 76 percent / NH₂OH*HCl; K₂CO₃ / ethanol / 4 h / Heating

With pyridine; ammonium hydroxide; hydroxylamine hydrochloride; potassium carbonate; trifluoroacetic anhydride; In methanol; ethanol;
DOI:10.1016/j.bmcl.2005.01.023