5-Chlorothiophene-3-carbonyl chloride

Base Information

Chemical Name:5-Chlorothiophene-3-carbonyl chloride
CAS No.:113471-08-2
Molecular Formula:C₅H₂Cl₂OS
Molecular Weight:181.042
Hs Code.:
DSSTox Substance ID:DTXSID90546144
Wikidata:Q82423878
Mol file:113471-08-2.mol

Synonyms:5-Chlorothiophene-3-carbonyl chloride;113471-08-2;3-Thiophenecarbonyl chloride, 5-chloro- (9CI);SCHEMBL1771714;DTXSID90546144

Suppliers and Price of 5-Chlorothiophene-3-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5-Chlorothiophene-3-carbonyl chloride

Chemical Property:

PSA：45.31000
LogP:2.78050
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:179.9203412
Heavy Atom Count:9
Complexity:128

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(SC=C1C(=O)Cl)Cl

Technology Process of 5-Chlorothiophene-3-carbonyl chloride

There total 2 articles about 5-Chlorothiophene-3-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 36157-42-3
2-chlorothiophene-4-carboxylic acid

: 113471-08-2
5-chloro-thiophene-3-carbonyl chloride

Guidance literature:: With thionyl chloride; In benzene;
DOI:10.1016/j.bmcl.2011.07.057

Reference yield:

: 113471-08-2
5-chloro-thiophene-3-carbonyl chloride

Guidance literature:: 5-Chlor-thiophen-3-carbonsaeure, SOCl2 (exotherm. Rk., dann Siedetemp., 4 Std.); nicht rein isoliert;

Reference yield:

: 113471-08-2
5-chloro-thiophene-3-carbonyl chloride

: 1351753-37-1
C₁₄H₁₁BrClN₃OS

Guidance literature:: Multi-step reaction with 3 steps

1: n-butyllithium / toluene

2: potassium permanganate; water; sodium hydrogencarbonate; magnesium sulfate / acetone

3: water; sodium carbonate / 1,4-dioxane; ethanol

With potassium permanganate; n-butyllithium; water; sodium hydrogencarbonate; sodium carbonate; magnesium sulfate; In 1,4-dioxane; ethanol; acetone; toluene;
DOI:10.1016/j.bmcl.2011.07.057