Technology Process of C40H58O3Si2
There total 2 articles about C40H58O3Si2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(2R)-6-(tert-butyldimethylsilanyloxy)-1-trityloxyhex-4-yn-2-ol;
With
silver nitrate; triethylamine;
In
tetrahydrofuran; N,N-dimethyl-formamide;
at 0 ℃;
for 0.166667h;
triisopropylsilyl chloride;
In
tetrahydrofuran; N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 12h;
DOI:10.1016/j.tet.2010.11.017
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: dmap; triethylamine / 9.5 h / 20 °C
2.1: silver nitrate; triethylamine / tetrahydrofuran; N,N-dimethyl-formamide / 0.17 h / 0 °C
2.2: 12 h / 0 - 20 °C
With
dmap; silver nitrate; triethylamine;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2010.11.017
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 3.33 h / -78 - -20 °C
2.1: quinoline; hydrogen / ethyl acetate / 2 h / 20 °C
3.1: dimethyl sulfoxide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / 4 h / 20 °C
4.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 0.83 h / 0 °C
5.1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 8 h / 0 - 20 °C
6.1: tris-(dibenzylideneacetone)dipalladium(0); ((diphenylphosphoryl)oxy)copper(I); triethyl phosphite / tetrahydrofuran; hexane / 20 °C
7.1: cerium(III) chloride heptahydrate / ethanol / 0.33 h / 20 °C
7.2: 1.5 h / -40 °C
With
quinoline; triethylsilane; sodium chlorite; tris-(dibenzylideneacetone)dipalladium(0); sodium dihydrogenphosphate; 2-methyl-but-2-ene; ((diphenylphosphoryl)oxy)copper(I); cerium(III) chloride heptahydrate; boron trifluoride diethyl etherate; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; hydrogen; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; triethyl phosphite; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; ethanol; hexane; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; tert-butyl alcohol;
6.1: Stille-type coupling;
DOI:10.1016/j.tet.2010.11.017
