ethyl (2R,3R,4S,5R)-3-benzyloxy-4,5-isopropylidenedioxy-2-[N-(diphenylmethylene)amino]hexanoate

Base Information

Chemical Name:ethyl (2R,3R,4S,5R)-3-benzyloxy-4,5-isopropylidenedioxy-2-[N-(diphenylmethylene)amino]hexanoate
CAS No.:186694-59-7
Molecular Formula:C₃₁H₃₅NO₅
Molecular Weight:501.623
Hs Code.:

Synonyms:ethyl (2R,3R,4S,5R)-3-benzyloxy-4,5-isopropylidenedioxy-2-[N-(diphenylmethylene)amino]hexanoate

Suppliers and Price of ethyl (2R,3R,4S,5R)-3-benzyloxy-4,5-isopropylidenedioxy-2-[N-(diphenylmethylene)amino]hexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl (2R,3R,4S,5R)-3-benzyloxy-4,5-isopropylidenedioxy-2-[N-(diphenylmethylene)amino]hexanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl (2R,3R,4S,5R)-3-benzyloxy-4,5-isopropylidenedioxy-2-[N-(diphenylmethylene)amino]hexanoate

There total 6 articles about ethyl (2R,3R,4S,5R)-3-benzyloxy-4,5-isopropylidenedioxy-2-[N-(diphenylmethylene)amino]hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 1013-88-3
Benzophenone imine

: 186694-55-3
ethyl (2R,3R,4S,5R)-2-amino-3-benzyloxy-4,5-isopropylidenedioxyhexanoate

: 186694-59-7
ethyl (2R,3R,4S,5R)-3-benzyloxy-4,5-isopropylidenedioxy-2-[N-(diphenylmethylene)amino]hexanoate

Guidance literature:: With toluene-4-sulfonic acid; In dichloromethane; for 14h; Ambient temperature;
DOI:10.1055/s-1997-696

Reference yield:

: 182216-93-9
(R)-((2R,5S)-3,6-Diethoxy-5-isopropyl-2,5-dihydro-pyrazin-2-yl)-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-methanol

: 186694-59-7
ethyl (2R,3R,4S,5R)-3-benzyloxy-4,5-isopropylidenedioxy-2-[N-(diphenylmethylene)amino]hexanoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: tetrahydrofuran / 0.5 h / 0 °C

1.2: 85 percent / Bu₄NI / tetrahydrofuran / 12 h / 20 °C

2.1: 88 percent / 0.25N HCl / 5 h / 20 °C

3.1: 81 percent / p-TsOH / CH₂Cl₂ / 14 h / 20 °C

With hydrogenchloride; toluene-4-sulfonic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0957-4166(02)00376-2

Reference yield:

: 186694-54-2
(3R,6S,1'R,2'S,3'R)-3-(1-benzyloxy-2,3-isopropylidenedioxybutyl)-2,5-diethoxy-3,6-dihydro-6-isopropylpyrazine

: 186694-59-7
ethyl (2R,3R,4S,5R)-3-benzyloxy-4,5-isopropylidenedioxy-2-[N-(diphenylmethylene)amino]hexanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / 0.25N HCl / 5 h / 20 °C

2: 81 percent / p-TsOH / CH₂Cl₂ / 14 h / 20 °C

With hydrogenchloride; toluene-4-sulfonic acid; In dichloromethane;
DOI:10.1016/S0957-4166(02)00376-2