2,5-Dimethyl-1,3-thiazole-4-carboxylic acid

Base Information

Chemical Name:2,5-Dimethyl-1,3-thiazole-4-carboxylic acid
CAS No.:113366-73-7
Molecular Formula:C6H7 N O2 S
Molecular Weight:157.193
Hs Code.:2934100090
European Community (EC) Number:817-297-5
DSSTox Substance ID:DTXSID60550758
Wikidata:Q82430189
Mol file:113366-73-7.mol

Synonyms:113366-73-7;2,5-dimethyl-1,3-thiazole-4-carboxylic acid;2,5-Dimethylthiazole-4-carboxylic acid;MFCD09881001;dimethyl-1,3-thiazole-4-carboxylic acid;2,5-Dimethyl-thiazole-4-carboxylic acid;SCHEMBL2216614;DTXSID60550758;AFHYBEFNQLGRFV-UHFFFAOYSA-N;2,5-Dimethylthiazole-4-carboxylicacid;AKOS005175142;AT21448;SY106914;VS-10626;CS-0205681;EN300-92060;Z1198236098;2,5-Dimethyl-1,3-thiazole-4-carboxylic acid, AldrichCPR

Suppliers and Price of 2,5-Dimethyl-1,3-thiazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,5-Dimethylthiazole-4-carboxylicAcid
1g
$ 1260.00

SynChem
2,5-Dimethyl-thiazole-4-carboxylic acid 95+%
1 g
$ 750.00

SynChem
2,5-Dimethyl-thiazole-4-carboxylic acid 95+%
250 mg
$ 250.00

Matrix Scientific
2,5-Dimethyl-1,3-thiazole-4-carboxylic acid
1g
$ 448.00

Matrix Scientific
2,5-Dimethyl-1,3-thiazole-4-carboxylic acid
500mg
$ 360.00

Matrix Scientific
2,5-Dimethyl-1,3-thiazole-4-carboxylic acid
5g
$ 830.00

Crysdot
2,5-Dimethylthiazole-4-carboxylicacid 95+%
5g
$ 823.00

ChemBridge Corporation
2,5-dimethyl-1,3-thiazole-4-carboxylicacid 95%
250 mg
$ 121.00

Biosynth Carbosynth
2,5-Dimethyl-1,3-thiazole-4-carboxylic acid
500 mg
$ 270.00

Biosynth Carbosynth
2,5-Dimethyl-1,3-thiazole-4-carboxylic acid
1 g
$ 400.00

Total 8 raw suppliers

Chemical Property of 2,5-Dimethyl-1,3-thiazole-4-carboxylic acid

Chemical Property:

Melting Point:171-173 °C
Boiling Point:306.2±22.0 °C(Predicted)
PKA:0.99±0.32(Predicted)
PSA：78.43000
Density:1.341±0.06 g/cm3(Predicted)
LogP:1.45810
Storage Temp.:2-8°C
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:157.01974964
Heavy Atom Count:10
Complexity:151

Purity/Quality:

97% ^*data from raw suppliers

2,5-Dimethylthiazole-4-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N=C(S1)C)C(=O)O
Uses 2,5-Dimethylthiazole-4-carboxylic Acid is a bioactive compound with potential antibacterial activity against Staphylococcus aureus.

Technology Process of 2,5-Dimethyl-1,3-thiazole-4-carboxylic acid

There total 1 articles about 2,5-Dimethyl-1,3-thiazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 137267-44-8
ethyl 2,5-dimethylthiazole-4-carboxylate

: 113366-73-7
2,5-dimethyl-1,3-thiazole-4-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; for 48h; Ambient temperature;

Reference yield: 87.0%

: 1092394-73-4
N-[6-(3-amino-4-methylphenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

: 113366-73-7
2,5-dimethyl-1,3-thiazole-4-carboxylic acid

: 1092391-88-2
N-[5-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)-2-methylphenyl]-2,5-dimethyl-1,3-thiazole-4-carboxamide

Guidance literature:: 2,5-dimethyl-1,3-thiazole-4-carboxylic acid; With thionyl chloride; oxalyl dichloride; In tetrahydrofuran; at 20 ℃; for 2h;

N-[6-(3-amino-4-methylphenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide; In N,N-dimethyl acetamide; at 20 ℃; for 2h;

With water; sodium hydrogencarbonate; In N,N-dimethyl acetamide;

Reference yield: 85.0%

: 1738-69-8
L-Leucine benzyl ester

: 113366-73-7
2,5-dimethyl-1,3-thiazole-4-carboxylic acid

: 1198280-66-8
(S)-benzyl 2-(2,5-dimethylthiazole-4-carboxamido)-4-methylpentanoate

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 60 ℃; for 0.75h; Microwave irradiation;
DOI:10.1021/jo9016265