3-Aminopyrazine-2,6-dicarbonitrile

Base Information

Chemical Name:3-Aminopyrazine-2,6-dicarbonitrile
CAS No.:113305-95-6
Molecular Formula:C₆H₃N₅
Molecular Weight:145.123
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90552583
Nikkaji Number:J331.347F
Wikidata:Q82432933
Mol file:113305-95-6.mol

Synonyms:3-AMINOPYRAZINE-2,6-DICARBONITRILE;113305-95-6;SCHEMBL1697950;DTXSID90552583;AKOS006287451

Suppliers and Price of 3-Aminopyrazine-2,6-dicarbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Aminopyrazine-2,6-dicarbonitrile 95+%
1g
$ 491.00

Chemenu
3-aminopyrazine-2,6-dicarbonitrile 95%
1g
$ 464.00

American Custom Chemicals Corporation
2-AMINO-3,5-DICYANOPYRAZINE 95.00%
10G
$ 7882.88

American Custom Chemicals Corporation
2-AMINO-3,5-DICYANOPYRAZINE 95.00%
5G
$ 4244.63

American Custom Chemicals Corporation
2-AMINO-3,5-DICYANOPYRAZINE 95.00%
1G
$ 930.30

Total 8 raw suppliers

Chemical Property of 3-Aminopyrazine-2,6-dicarbonitrile

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:221-222 °C(Solv: ethanol (64-17-5))
Refractive Index:1.625
Boiling Point:395.548°C at 760 mmHg
PKA:-0.79±0.10(Predicted)
Flash Point:193.021°C
PSA：99.38000
Density:1.462g/cm³
LogP:0.38336
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:145.03884512
Heavy Atom Count:11
Complexity:230

Purity/Quality:

98%min ^*data from raw suppliers

3-Aminopyrazine-2,6-dicarbonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(N=C(C(=N1)N)C#N)C#N

Technology Process of 3-Aminopyrazine-2,6-dicarbonitrile

There total 2 articles about 3-Aminopyrazine-2,6-dicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 151-50-8
potassium cyanide

: 24241-18-7
2-amino-3,5-dibromopyrazine

: 113305-95-6
3-aminopyrazine-2,6-dicarbonitrile

: 17231-51-5
2-amino-5-bromo-3-cyanopyrazine

Guidance literature:: With copper(l) iodide; 18-crown-6 ether; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; for 1h; Heating;

Reference yield: 9.0%

: 24241-18-7
2-amino-3,5-dibromopyrazine

: 113305-95-6
3-aminopyrazine-2,6-dicarbonitrile

: 17231-51-5
2-amino-5-bromo-3-cyanopyrazine

Guidance literature:: In N,N-dimethyl-formamide; at 120 - 130 ℃; for 2.5h;
DOI:10.1055/s-1990-26972

Reference yield:

: 113305-95-6
3-aminopyrazine-2,6-dicarbonitrile

: 1351237-64-3
7-amino-2-cyano-N-(5-(3-(2-cyanopropan-2-yl)benzamido)-2-methylphenyl)thieno[2,3-b]pyrazine-6-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: copper(ll) bromide; tert.-butylnitrite / acetonitrile / 4 h / 60 - 70 °C

2: potassium carbonate / ethanol / 1 h / 40 °C

With tert.-butylnitrite; potassium carbonate; copper(ll) bromide; In ethanol; acetonitrile; 1: Sandmeyer Reaction;