6-(m-Tolyl)pyridazin-3-amine

Base Information

• Chemical Name: 6-(m-Tolyl)pyridazin-3-amine
• CAS No.: 113121-50-9
• Molecular Formula: C₁₁H₁₁N₃
• Molecular Weight: 185.228
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID00573340
• Nikkaji Number: J1.483.172J
• Wikidata: Q82462039
• Mol file: 113121-50-9.mol

Synonyms:6-(m-Tolyl)pyridazin-3-amine;113121-50-9;6-(3-Methylphenyl)pyridazin-3-amine;3-Pyridazinamine, 6-(3-methylphenyl)-;3-Pyridazinamine,6-(3-methylphenyl)-;SCHEMBL16826158;DTXSID00573340;AKOS011483806

Chemical Property of 6-(m-Tolyl)pyridazin-3-amine

Chemical Property:

• Vapor Pressure: 1.42E-06mmHg at 25°C
• Refractive Index: 1.619
• Boiling Point: 399°C at 760 mmHg
• Flash Point: 223.8°C
• PSA: 51.80000
• Density: 1.159g/cm³
• LogP: 2.61540
• Storage Temp.: 2-8°C
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 185.095297364
• Heavy Atom Count: 14
• Complexity: 183

Purity/Quality:

98% ^*data from raw suppliers

3-AMINO-6-(3-TOLYL)PYRIDAZINE 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC=C1)C2=NN=C(C=C2)N

Technology Process of 6-(m-Tolyl)pyridazin-3-amine

There total 2 articles about 6-(m-Tolyl)pyridazin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

6-chloro-pyridazin-3-ylamine (5469-69-2) + m-tolylboronic acid (17933-03-8) → 3-amino-6-(3-methylphenyl)pyridazine (113121-50-9)

Guidance literature:

6-chloro-pyridazin-3-ylamine; m-tolylboronic acid; With sodium carbonate; In ethanol; toluene; for 0.5h;

tris(triphenylphosphano)palladium; In ethanol; toluene; at 110 ℃; for 32h;

DOI:10.1016/S0040-4039(01)00134-4

Reference yield:

→ 3-amino-6-(3-methylphenyl)pyridazine (113121-50-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; for 18h; Reflux;

upstream raw materials:

6-chloro-pyridazin-3-ylamine

m-tolylboronic acid