C₁₄H₁₃NO₃

Base Information

• Chemical Name: C₁₄H₁₃NO₃
• CAS No.: 1361938-32-0
• Molecular Formula: C₁₄H₁₃NO₃
• Molecular Weight: 243.262
• Mol file: 1361938-32-0.mol

Synonyms:C₁₄H₁₃NO₃

Chemical Property of C₁₄H₁₃NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₃NO₃

There total 6 articles about C₁₄H₁₃NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H17NO3 (1361938-30-8) → C14H13NO3 (1361938-32-0)

Guidance literature:

With water; lithium hydroxide; In ethanol; at 60 ℃;

Reference yield:

ethyl 3-hydroxy-3-methyl-1-p-toluenesulfonylpyrrolidine-2-carboxylate (3284-52-4) → C14H13NO3 (1361938-32-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: pyridine; trichlorophosphate / 72 h / 20 °C / Cooling with ice

2.1: sodium ethanolate / ethanol

3.1: zinc(II) chloride / 1,2-dichloro-ethane / 2 h / Reflux

4.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / Cooling with ice

4.2: 20 °C / Cooling with ice

5.1: lithium hydroxide; water / ethanol / 60 °C

With pyridine; water; sodium ethanolate; sodium hydride; zinc(II) chloride; lithium hydroxide; trichlorophosphate; In ethanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide;

Reference yield:

3-methyl-1-p-toluenesulfonyl-2,5-dihydro-1H-pyrrole-2-carboxylic acid ethyl ester (3284-53-5) → C14H13NO3 (1361938-32-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium ethanolate / ethanol

2.1: zinc(II) chloride / 1,2-dichloro-ethane / 2 h / Reflux

3.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / Cooling with ice

3.2: 20 °C / Cooling with ice

4.1: lithium hydroxide; water / ethanol / 60 °C

With water; sodium ethanolate; sodium hydride; zinc(II) chloride; lithium hydroxide; In ethanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide;

upstream raw materials:

ethyl 3-hydroxy-3-methyl-1-p-toluenesulfonylpyrrolidine-2-carboxylate

3-methyl-1-p-toluenesulfonyl-2,5-dihydro-1H-pyrrole-2-carboxylic acid ethyl ester

ethyl 3-methyl-1H-pyrrole-2-carboxylate

ethyl 4-benzoyl-3-methylpyrrole-2-carboxylate

Refernces