1-(tert-butyl-diphenyl-silanyloxy)-3,11-dimethyl-7-methylene-dodeca-2,10-dien-6-ol

Base Information

Chemical Name:1-(tert-butyl-diphenyl-silanyloxy)-3,11-dimethyl-7-methylene-dodeca-2,10-dien-6-ol
CAS No.:916260-45-2
Molecular Formula:C₃₁H₄₄O₂Si
Molecular Weight:476.775
Hs Code.:

1-(<i>tert</i>-butyl-diphenyl-silanyloxy)-3,11-dimethyl-7-methylene-dodeca-2,10-dien-6-ol

Synonyms:1-(tert-butyl-diphenyl-silanyloxy)-3,11-dimethyl-7-methylene-dodeca-2,10-dien-6-ol

Suppliers and Price of 1-(tert-butyl-diphenyl-silanyloxy)-3,11-dimethyl-7-methylene-dodeca-2,10-dien-6-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(tert-butyl-diphenyl-silanyloxy)-3,11-dimethyl-7-methylene-dodeca-2,10-dien-6-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(tert-butyl-diphenyl-silanyloxy)-3,11-dimethyl-7-methylene-dodeca-2,10-dien-6-ol

There total 2 articles about 1-(tert-butyl-diphenyl-silanyloxy)-3,11-dimethyl-7-methylene-dodeca-2,10-dien-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 916260-44-1
2-bromo-6-methyl-1,5-heptadiene

: 139109-02-7
(E)-6-((tert-butyldiphenylsilyl)oxy)-4-methylhex-4-enal

: 916260-45-2
1-(tert-butyl-diphenyl-silanyloxy)-3,11-dimethyl-7-methylene-dodeca-2,10-dien-6-ol

Guidance literature:: 2-bromo-6-methyl-1,5-heptadiene; With tert.-butyl lithium; In diethyl ether; pentane; at -78 - -20 ℃; for 4h;

(E)-6-((tert-butyldiphenylsilyl)oxy)-4-methylhex-4-enal; In diethyl ether; at -78 ℃; for 2h;
DOI:10.1021/ja066336b

Reference yield:

: 89487-33-2
prenylmagnesium bromide

: 916260-45-2
1-(tert-butyl-diphenyl-silanyloxy)-3,11-dimethyl-7-methylene-dodeca-2,10-dien-6-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: CuCN / tetrahydrofuran / 0.5 h / -78 °C

1.2: 91 percent / tetrahydrofuran / 2 h / -78 °C

2.1: t-BuLi / diethyl ether; pentane / 4 h / -78 - -20 °C

2.2: 90 percent / diethyl ether / 2 h / -78 °C

With tert.-butyl lithium; In tetrahydrofuran; diethyl ether; pentane;
DOI:10.1021/ja066336b

Reference yield: 61.0%

: 916260-45-2
1-(tert-butyl-diphenyl-silanyloxy)-3,11-dimethyl-7-methylene-dodeca-2,10-dien-6-ol

: 66222-29-5
tri-n-butylstannylmethyl iodide

: 916260-46-3
9-(tert-butyl-diphenyl-silanyloxy)-7-methyl-3-(4-methyl-pent-3-enyl)-nona-3,7-dien-1-ol

Guidance literature:: 1-(tert-butyl-diphenyl-silanyloxy)-3,11-dimethyl-7-methylene-dodeca-2,10-dien-6-ol; With potassium hydride; In tetrahydrofuran; at -40 - -20 ℃; for 0.5h;

tri-n-butylstannylmethyl iodide; In diethyl ether; at -20 - 0 ℃; for 16h;

With n-butyllithium; In tetrahydrofuran; Petroleum ether; at -78 ℃; for 3h;
DOI:10.1021/ja066336b