15-DEOXY-DELTA12,14-PROSTAGLANDIN A2

Base Information

• Chemical Name: 15-DEOXY-DELTA12,14-PROSTAGLANDIN A2
• CAS No.: 112839-31-3
• Molecular Formula: C₂₀H₂₈O₃
• Molecular Weight: 316.441
• Mol file: 112839-31-3.mol

Synonyms:9-OXO-PROSTA-5Z, 10, 12Z, 14E-TETRAEN-1-OIC ACID;15-DEOXY-DELTA12,14-PROSTAGLANDIN A2

Chemical Property of 15-DEOXY-DELTA12,14-PROSTAGLANDIN A2

Chemical Property:

• Boiling Point: 499.0±14.0 °C(Predicted)
• PKA: 4.75±0.10(Predicted)
• PSA: 54.37000
• Density: 1.066±0.06 g/cm3(Predicted)
• LogP: 5.00560

Purity/Quality:

99%,98%, ^*data from raw suppliers

15-deoxy-Δ12,14-Prostaglandin A2 ≥98% (isomer mixture) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 15-DEOXY-DELTA12,14-PROSTAGLANDIN A2

There total 2 articles about 15-DEOXY-DELTA12,14-PROSTAGLANDIN A2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

13,14-cis-PGA2 (55392-90-0,58685-03-3,63141-11-7,64338-92-7) → 15d-PGA2 (112839-31-3)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: (hydrolysis)

In diethyl ether;

DOI:10.1021/ja00460a037

Reference yield:

(Z)-7-[(1R,2S)-2-((Z)-(R)-3-Acetoxy-oct-1-enyl)-5-oxo-cyclopent-3-enyl]-hept-5-enoic acid methyl ester (25488-91-9,36323-03-2,58685-04-4,59659-05-1,64338-95-0) → 15d-PGA2 (112839-31-3)

Guidance literature:

(hydrolysis);

DOI:10.1021/ja00460a037

upstream raw materials:

(Z)-7-[(1R,2S)-2-((Z)-(R)-3-Acetoxy-oct-1-enyl)-5-oxo-cyclopent-3-enyl]-hept-5-enoic acid methyl ester

13,14-cis-PGA₂

Refernces