2-formylphenyl nicotinate

Base Information

• Chemical Name: 2-formylphenyl nicotinate
• CAS No.: 7739-94-8
• Molecular Formula: C₁₃H₉NO₃
• Molecular Weight: 227.219
• Mol file: 7739-94-8.mol

Synonyms:2-formylphenyl nicotinate

Chemical Property of 2-formylphenyl nicotinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-formylphenyl nicotinate

There total 2 articles about 2-formylphenyl nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

3-pyridinecarboxaldehyde (500-22-1) + salicylaldehyde (90-02-8) → 2-formylphenyl nicotinate (7739-94-8)

Guidance literature:

With tert.-butylhydroperoxide; copper diacetate; In water; at 80 ℃; for 2h; Schlenk technique;

DOI:10.1016/j.tetlet.2015.06.024

Reference yield:

pyridine-3-carbonyl chloride hydrochloride (20260-53-1) + salicylaldehyde (90-02-8) → 2-formylphenyl nicotinate (7739-94-8)

Guidance literature:

With pyridine; chloroform;

DOI:10.1002/ardp.19582910704

Reference yield: 75.0%

2-formylphenyl nicotinate (7739-94-8) + 4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one (83-07-8) → 2-[(Z)-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)iminomethyl]phenyl pyridine-3-carboxylate

Guidance literature:

With acetic acid; In methanol; for 1h; Reflux;

DOI:10.1134/S1070363220080095

upstream raw materials:

pyridine-3-carbonyl chloride hydrochloride

salicylaldehyde

3-pyridinecarboxaldehyde