(E)-5-[2-(4-chlorophenyl)ethenyl]-1,3-dimethoxyphenylethene

Base Information

Chemical Name:(E)-5-[2-(4-chlorophenyl)ethenyl]-1,3-dimethoxyphenylethene
CAS No.:1032508-03-4
Molecular Formula:C₁₆H₁₅ClO₂
Molecular Weight:274.747
Hs Code.:
Mol file:1032508-03-4.mol

Synonyms:(E)-5-[2-(4-chlorophenyl)ethenyl]-1,3-dimethoxyphenylethene

Suppliers and Price of (E)-5-[2-(4-chlorophenyl)ethenyl]-1,3-dimethoxyphenylethene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
PDM-11 >98%
1 g
$ 1300.00

Cayman Chemical
PDM 11 ≥98%
100mg
$ 173.00

Cayman Chemical
PDM 11 ≥98%
25mg
$ 53.00

Cayman Chemical
PDM 11 ≥98%
10mg
$ 22.00

Cayman Chemical
PDM 11 ≥98%
50mg
$ 98.00

ApexBio Technology
PDM11
50mg
$ 125.00

ApexBio Technology
PDM11
25mg
$ 67.00

ApexBio Technology
PDM11
100mg
$ 222.00

AK Scientific
(E)-4'-Chloro-3,5-dimethoxystilbene
25mg
$ 164.00

Total 8 raw suppliers

Chemical Property of (E)-5-[2-(4-chlorophenyl)ethenyl]-1,3-dimethoxyphenylethene

Chemical Property:

Melting Point:65-66 °C
Boiling Point:409.1±35.0 °C(Predicted)
Density:1.181±0.06 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

PDM-11 >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description PDM 11 is a derivative of the antioxidant trans-resveratrol that is inactive in vitro in assays of resveratrol activity. It does not activate quinone reductase 1, inhibit quinone reductase 2, or affect nitric oxide production or quenching of free radicals. It does not interact with estrogen receptors or affect the activity of COX-1 and COX-2. PDM 11 does not affect proliferation of K562, HT-29, and HepG2 cells.
Uses PDM-11 is a derivative of Resveratrol (R150000(P)) with antioxidant activity that can inhibit intestinal epithelial cancer Caco-?2 cell growth. It has a stronger antagonist affinity for arylhydrocarbon receptors (AhR) than resveratrol.

Technology Process of (E)-5-[2-(4-chlorophenyl)ethenyl]-1,3-dimethoxyphenylethene

There total 10 articles about (E)-5-[2-(4-chlorophenyl)ethenyl]-1,3-dimethoxyphenylethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1073-67-2,24991-47-7
4-vinylbenzyl chloride

: 192182-54-0
3,5-dimethoxyphenylboronic acid

: 1032508-03-4
(E)-5-[2-(4-chlorophenyl)ethenyl]-1,3-dimethoxyphenylethene

Guidance literature:: With dichloro bis(acetonitrile) palladium(II); oxygen; sodium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 3h;
DOI:10.1016/j.bmcl.2016.07.018

Reference yield: 68.0%

: 86255-43-8
trans-1-(3,5-Dimethoxyphenyl)-2-nitroethylene

: 1073-69-4
N-4-chlorophenylhydrazine

: 1032508-03-4
(E)-5-[2-(4-chlorophenyl)ethenyl]-1,3-dimethoxyphenylethene

Guidance literature:: trans-1-(3,5-Dimethoxyphenyl)-2-nitroethylene; With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In acetonitrile; at 20 ℃; for 0.166667h;

N-4-chlorophenylhydrazine; In acetonitrile; at 20 ℃; for 4.5h; diastereoselective reaction;
DOI:10.1039/c7nj04701k

Reference yield: 32.5%

: 104-88-1
4-chlorobenzaldehyde

: 108957-75-1
diethyl 3,5-dimethoxybenzylphosphonate

: 1032508-03-4
(E)-5-[2-(4-chlorophenyl)ethenyl]-1,3-dimethoxyphenylethene

Guidance literature:: diethyl 3,5-dimethoxybenzylphosphonate; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 1h;

4-chlorobenzaldehyde; In tetrahydrofuran; at 0 - 20 ℃; for 17h;
DOI:10.14233/ajchem.2014.16226