Technology Process of C19H22FNO3
There total 6 articles about C19H22FNO3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
magnesium chloride; catalase from bovine liver;
In
dimethyl sulfoxide;
at 40 ℃;
for 24h;
pH=9;
enantioselective reaction;
Darkness;
Enzymatic reaction;
DOI:10.1002/chem.201201895
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium iodide; potassium hydroxide / ethanol / 20 °C
2.1: oxalyl dichloride; N,N-dimethyl-formamide / toluene / 3 h / Inert atmosphere
3.1: sodium hydroxide / chloroform; water / 16 h / 20 °C / Cooling with ice
4.1: trichlorophosphate / acetonitrile / 3 h / Reflux; Inert atmosphere
4.2: 16 h / 20 °C / Inert atmosphere; Cooling with ice
5.1: acetic acid; hydrogen; palladium on activated charcoal / methanol / 16 h / 760.05 Torr
6.1: catalase from bovine liver; magnesium chloride / dimethyl sulfoxide / 24 h / 40 °C / pH 9 / Darkness; Enzymatic reaction
With
oxalyl dichloride; palladium on activated charcoal; hydrogen; acetic acid; N,N-dimethyl-formamide; sodium iodide; potassium hydroxide; sodium hydroxide; magnesium chloride; catalase from bovine liver; trichlorophosphate;
In
methanol; ethanol; chloroform; water; dimethyl sulfoxide; toluene; acetonitrile;
DOI:10.1002/chem.201201895
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: oxalyl dichloride; N,N-dimethyl-formamide / toluene / 3 h / Inert atmosphere
2.1: sodium hydroxide / chloroform; water / 16 h / 20 °C / Cooling with ice
3.1: trichlorophosphate / acetonitrile / 3 h / Reflux; Inert atmosphere
3.2: 16 h / 20 °C / Inert atmosphere; Cooling with ice
4.1: acetic acid; hydrogen; palladium on activated charcoal / methanol / 16 h / 760.05 Torr
5.1: catalase from bovine liver; magnesium chloride / dimethyl sulfoxide / 24 h / 40 °C / pH 9 / Darkness; Enzymatic reaction
With
oxalyl dichloride; palladium on activated charcoal; hydrogen; acetic acid; N,N-dimethyl-formamide; sodium hydroxide; magnesium chloride; catalase from bovine liver; trichlorophosphate;
In
methanol; chloroform; water; dimethyl sulfoxide; toluene; acetonitrile;
DOI:10.1002/chem.201201895