(-)-Diisopinocampheyl Chloroborane (97%)

Base Information

Chemical Name:(-)-Diisopinocampheyl Chloroborane (97%)
CAS No.:112246-74-9
Molecular Formula:C₂₀H₃₄BBr
Molecular Weight:365.205
Hs Code.:
European Community (EC) Number:624-786-5
Mol file:112246-74-9.mol

Synonyms:(+)-DIP bromide;(-)-Diisopinocampheyl Chloroborane (97%);112246-74-9

Suppliers and Price of (-)-Diisopinocampheyl Chloroborane (97%)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(+)-DIP-BROMIDE 95.00%
5MG
$ 505.22

Total 5 raw suppliers

Chemical Property of (-)-Diisopinocampheyl Chloroborane (97%)

Chemical Property:

Vapor Pressure:1.93E-05mmHg at 25°C
Melting Point:62-72 °C(lit.)
Refractive Index:1.515
Boiling Point:373.4°Cat760mmHg
Flash Point:179.6°C
PSA：0.00000
Density:1.12g/cm³
LogP:6.51740
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:2
Exact Mass:364.19369
Heavy Atom Count:22
Complexity:428

Purity/Quality:

98% ^*data from raw suppliers

(+)-DIP-BROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C
Statements: 34
Safety Statements: 26-27-28-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1CC2CC(C1C)C2(C)C)(C3CC4CC(C3C)C4(C)C)Br
Isomeric SMILES:B([C@H]1C[C@H]2C[C@@H]([C@@H]1C)C2(C)C)([C@H]3C[C@H]4C[C@@H]([C@@H]3C)C4(C)C)Br
Uses (+)?-?DIP-?Bromide is a chiral catalyst used in organic synthesis, used in asymmetric DIels-Alder reactions as well as in the Pictet-Spengler reaction.

Technology Process of (-)-Diisopinocampheyl Chloroborane (97%)

There total 2 articles about (-)-Diisopinocampheyl Chloroborane (97%) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 21932-54-7
diisopinocampheylborane

: 104114-70-7,112246-74-9
B-bromodiisopinocampheylborane

Guidance literature:: With hydrogen bromide; In pentane; prepn. of a suspn. of freshly prepared borane in anhyd. pentane under N2, cooling to 0°C while a slow stream of HBr is passed through under stirring, stopping of stirring and standing at 0°C for 2-3 h; transferring of pentane soln. by cannula, solvent removal in vac., viscous residue is solidified by standing, recrystn. from cold pentane;

Reference yield:

: 21947-87-5
L-diisopinocampheylborane

: 175892-48-5,112246-74-9
B-bromodiisopinocampheylborane

Guidance literature:: With hydrogen bromide; In pentane; 0°C;;
DOI:10.1021/ja00226a050

Reference yield: 71.0%

: 104114-70-7,112246-74-9
B-bromodiisopinocampheylborane

: 285-67-6,149827-17-8
(1S,5R)-6-Oxa-bicyclo[3.1.0]hexane

: (C₁₀H₁₇)BNH(C₂H₄O)2

: 122673-88-5
(1R,2R)-2-bromocyclopentan-1-ol

Guidance literature:: With butyraldehyde; 2,2'-iminobis[ethanol]; In pentane; cooling of a pentane soln. of 1.0 M borane to -100°C (under N2), dropwise addn. of epoxide in pentane, addn. of butyraldehyde, warming to room temp., diluting with pentane and then addn. of diethanolamine; monitored bei (11)B NMR, filtn. of B-complex, washing of the filtrate with water, drying with anhyd. Na2SO4, concn. in vac., flash chromy. on silica gel (ether/hexane), distn. of halohydrine, 48 % ee;