5-[(2S)-2-Aminopropyl]-2-methoxybenzenesulfonamide;hydrochloride

Base Information

• Chemical Name: 5-[(2S)-2-Aminopropyl]-2-methoxybenzenesulfonamide;hydrochloride
• CAS No.: 112101-77-6
• Molecular Formula: C₁₀H₁₆N₂O₃S*ClH
• Molecular Weight: 280.776
• European Community (EC) Number: 601-158-9
• Mol file: 112101-77-6.mol

Synonyms:112101-77-6;5-[(2S)-2-Aminopropyl]-2-methoxybenzenesulfonamide;hydrochloride;(S)-3-(4'-Methoxy-3'-sulfonamidophenyl)-2-propylamine Hydrochloride;(S)-3-(4 inverted exclamation mark -Methoxy-3 inverted exclamation mark -sulfonamidophenyl)-2-propylamine Hydrochloride

Chemical Property of 5-[(2S)-2-Aminopropyl]-2-methoxybenzenesulfonamide;hydrochloride

Chemical Property:

• PSA: 103.79000
• LogP: 3.51570
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 280.0648413
• Heavy Atom Count: 17
• Complexity: 313

Purity/Quality:

98%Min ^*data from raw suppliers

(S)-3-(4’-Methoxy-3’-sulfonamidophenyl)-2-propylamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CC1=CC(=C(C=C1)OC)S(=O)(=O)N)N.Cl
• Isomeric SMILES: C[C@@H](CC1=CC(=C(C=C1)OC)S(=O)(=O)N)N.Cl
• Uses: (S)-3-(4’-Methoxy-3’-sulfonamidophenyl)-2-propylamine Hydrochloride is a (phenoxyethylamino)propylbenzenesulfonamide derivatives and potential α-blockers.

Technology Process of 5-[(2S)-2-Aminopropyl]-2-methoxybenzenesulfonamide;hydrochloride

There total 1 articles about 5-[(2S)-2-Aminopropyl]-2-methoxybenzenesulfonamide;hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H22N2O4S2 → (R)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide hydrochloride (86225-65-2) + (S)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide hydrochloride (112101-77-6,86225-65-2)

Guidance literature:

C₁₄H₂₂N₂O₄S₂; With sodium tetrahydroborate; In tetrahydrofuran; at -48 ℃; Inert atmosphere;

With hydrogenchloride; In methanol; optical yield given as %ee;

DOI:10.1080/00397910802519216

Refernces