(2S,4S,5R)-5-(4-bromophenyl)-4-tert-butoxy-carbonyl-1-[(2'S)-N-methyl-N-tosylphenylalanyl]-2-methoxy-carbonylpyrrolidine

Base Information

Chemical Name:(2S,4S,5R)-5-(4-bromophenyl)-4-tert-butoxy-carbonyl-1-[(2'S)-N-methyl-N-tosylphenylalanyl]-2-methoxy-carbonylpyrrolidine
CAS No.:1416475-26-7
Molecular Formula:C₃₄H₃₉BrN₂O₇S
Molecular Weight:699.663
Hs Code.:

Synonyms:(2S,4S,5R)-5-(4-bromophenyl)-4-tert-butoxy-carbonyl-1-[(2'S)-N-methyl-N-tosylphenylalanyl]-2-methoxy-carbonylpyrrolidine

Suppliers and Price of (2S,4S,5R)-5-(4-bromophenyl)-4-tert-butoxy-carbonyl-1-[(2'S)-N-methyl-N-tosylphenylalanyl]-2-methoxy-carbonylpyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2S,4S,5R)-5-(4-bromophenyl)-4-tert-butoxy-carbonyl-1-[(2'S)-N-methyl-N-tosylphenylalanyl]-2-methoxy-carbonylpyrrolidine

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (2S,4S,5R)-5-(4-bromophenyl)-4-tert-butoxy-carbonyl-1-[(2'S)-N-methyl-N-tosylphenylalanyl]-2-methoxy-carbonylpyrrolidine

There total 1 articles about (2S,4S,5R)-5-(4-bromophenyl)-4-tert-butoxy-carbonyl-1-[(2'S)-N-methyl-N-tosylphenylalanyl]-2-methoxy-carbonylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5-(4-bromophenyl)-4-tert-butoxycarbonyl-2-methoxycarbonylpyrrolidine

: 1416475-17-6
N-Methyl-N-tosyl-(S)-phenylalanyl chloride

: 1416475-21-2
(2R,4R,5S)-5-(4-bromophenyl)-4-tert-butoxy-carbonyl-1-[(2'S)-N-methyl-N-tosylphenylalanyl]-2-methoxy-carbonylpyrrolidine

: 1416475-26-7
(2S,4S,5R)-5-(4-bromophenyl)-4-tert-butoxy-carbonyl-1-[(2'S)-N-methyl-N-tosylphenylalanyl]-2-methoxy-carbonylpyrrolidine

Guidance literature:: With N,N-diethylaniline; In dichloromethane; at 20 ℃; for 6h; Solvent; Overall yield = 58 %; Overall yield = 0.324 g; diastereoselective reaction; Resolution of racemate;
DOI:10.1016/j.tetasy.2012.10.020