(S)-3-P-MESYLOXYTETRAHYDROFURAN

Base Information Edit

Chemical Name:(S)-3-P-MESYLOXYTETRAHYDROFURAN
CAS No.:112052-11-6
Molecular Formula:C11H14 O4 S
Molecular Weight:242.296
Hs Code.:
Mol file:112052-11-6.mol

Synonyms:3-Furanol,tetrahydro-, 4-methylbenzenesulfonate, (3S)- (9CI); 3-Furanol, tetrahydro-,4-methylbenzenesulfonate, (S)-

Suppliers and Price of (S)-3-P-MESYLOXYTETRAHYDROFURAN

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 42 raw suppliers

Chemical Property of (S)-3-P-MESYLOXYTETRAHYDROFURAN Edit

Chemical Property:

PSA：60.98000
LogP:2.57000

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 3-(4-Methylbenzenesulfonate) (3S)-Tetrahydro-3-furanol is an intermediate used in the synthesis of 3’’’-Epi-Empagliflozin (E586000), which is an impurity of Empagliflozin (E521510) which is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats.

Technology Process of (S)-3-P-MESYLOXYTETRAHYDROFURAN

There total 6 articles about (S)-3-P-MESYLOXYTETRAHYDROFURAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 86087-23-2,84921-89-1,864447-89-2
(S)-3-hydroxytetyrahydrofurane

: 98-59-9
p-toluenesulfonyl chloride

: 112052-11-6
toluene-4-sulfonic acid (S)-(tetrahydrofuran-3-yl)ester

Guidance literature:: With 1H-imidazole; dmap; In dichloromethane; at 20 ℃; for 16h;

Reference yield: 96.0%

: 86087-23-2,84921-89-1,864447-89-2
(S)-3-hydroxytetyrahydrofurane

: 104-15-4
toluene-4-sulfonic acid

: 112052-11-6
toluene-4-sulfonic acid (S)-(tetrahydrofuran-3-yl)ester

Guidance literature:: (S)-3-hydroxytetyrahydrofurane; With dmap; triethylamine; In dichloromethane; at 0 ℃; for 0.166667h;

toluene-4-sulfonic acid; at 20 - 50 ℃; for 1.66667h;