(1R)-benzyl 3-(tert-butoxycarbonylamino)-3-(2-oxoethyl)cyclopentanecarboxylate

Base Information

Chemical Name:(1R)-benzyl 3-(tert-butoxycarbonylamino)-3-(2-oxoethyl)cyclopentanecarboxylate
CAS No.:1287745-37-2
Molecular Formula:C₂₀H₂₇NO₅
Molecular Weight:361.438
Hs Code.:

Synonyms:(1R)-benzyl 3-(tert-butoxycarbonylamino)-3-(2-oxoethyl)cyclopentanecarboxylate

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Chemical Property of (1R)-benzyl 3-(tert-butoxycarbonylamino)-3-(2-oxoethyl)cyclopentanecarboxylate

Chemical Property:

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Technology Process of (1R)-benzyl 3-(tert-butoxycarbonylamino)-3-(2-oxoethyl)cyclopentanecarboxylate

There total 3 articles about (1R)-benzyl 3-(tert-butoxycarbonylamino)-3-(2-oxoethyl)cyclopentanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1287745-35-0
(1R)-benzyl 3-allyl-3-(tert-butoxycarbonylamino)-cyclopentanecarboxylate

: 1287745-37-2
(1R)-benzyl 3-(tert-butoxycarbonylamino)-3-(2-oxoethyl)cyclopentanecarboxylate

Guidance literature:: With ozone; In dichloromethane; at -78 ℃;

Reference yield:

: 1287745-28-1
(1R)-benzyl 3-allyl-3-aminocyclopentanecarboxylate

: 1287745-37-2
(1R)-benzyl 3-(tert-butoxycarbonylamino)-3-(2-oxoethyl)cyclopentanecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 16 h / 20 °C

2: ozone / dichloromethane / -78 °C

With ozone; triethylamine; In dichloromethane;

Reference yield:

: 1287745-32-7
(R)-benzyl 3-oxocyclopentanecarboxylate

: 1287745-37-2
(1R)-benzyl 3-(tert-butoxycarbonylamino)-3-(2-oxoethyl)cyclopentanecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: ammonia / methanol / 16 h / 20 °C

2: triethylamine / dichloromethane / 16 h / 20 °C

3: ozone / dichloromethane / -78 °C

With ammonia; ozone; triethylamine; In methanol; dichloromethane;