2-(2,4,5-Trifluorophenyl)acetaldehyde

Base Information

Chemical Name:2-(2,4,5-Trifluorophenyl)acetaldehyde
CAS No.:111991-20-9
Molecular Formula:C8H5 F3 O
Molecular Weight:174.122
Hs Code.:2913000090
DSSTox Substance ID:DTXSID60695178
Wikidata:Q82624266
Mol file:111991-20-9.mol

Synonyms:111991-20-9;2-(2,4,5-TRIFLUOROPHENYL)ACETALDEHYDE;(2,4,5-Trifluorophenyl)acetaldehyde;Benzeneacetaldehyde,2,4,5-trifluoro-;SCHEMBL2556351;DTXSID60695178;2,4,5-Trifluorophenyl acetaldehyde;AKOS006307931;Benzeneacetaldehyde, 2,4,5-trifluoro-;CS-0266379;EN300-1725348

Suppliers and Price of 2-(2,4,5-Trifluorophenyl)acetaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(2,4,5-Trifluorophenyl)acetaldehyde
2.5g
$ 990.00

Rieke Metals
(2,4,5-Trifluorophenyl)acetaldehyde
5g
$ 1668.00

Rieke Metals
(2,4,5-Trifluorophenyl)acetaldehyde
1g
$ 494.00

American Custom Chemicals Corporation
2-(2,4,5-TRIFLUOROPHENYL)ACETALDEHYDE 95.00%
5MG
$ 499.39

Total 28 raw suppliers

Chemical Property of 2-(2,4,5-Trifluorophenyl)acetaldehyde

Chemical Property:

Boiling Point:196.8±35.0 °C(Predicted)
PSA：17.07000
Density:1.317±0.06 g/cm3(Predicted)
LogP:1.84530
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:174.02924926
Heavy Atom Count:12
Complexity:162

Purity/Quality:

99%, ^*data from raw suppliers

2-(2,4,5-Trifluorophenyl)acetaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CC(=C1F)F)F)CC=O
Uses 2-(2,4,5-Trifluorophenyl)acetaldehyde is derived from 2,4,5-Trifluorobenzeneacetic Acid (T792625), which is used in the synthesis of EGFR/ErbB-2-kinase inhibitors. Also used in the synthesis of new imidazopyrazinone derivatives as potnetial dipeptidyl peptidase IV inhibitors.

Technology Process of 2-(2,4,5-Trifluorophenyl)acetaldehyde

There total 8 articles about 2-(2,4,5-Trifluorophenyl)acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 111991-20-9
2-(2,4,5-trifluorophenyl)acetaldehyde

Guidance literature:: With 4-methyl-morpholine; 1,3,5-Triazine; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride hydrate; In tetrahydrofuran; water; at 25 ℃; for 1h;

With 5%-palladium/activated carbon; hydrogen; In tetrahydrofuran; water; at 25 ℃; for 19h; under 760.051 Torr;

Reference yield: 94.0%

: 883267-70-7
2-(2,4,5-trifluorophenyl)ethanol

: 111991-20-9
2-(2,4,5-trifluorophenyl)acetaldehyde

Guidance literature:: With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; potassium bromide; In dichloromethane; water; at 0 ℃; for 1h;