benzyl-4',5-dimethylspiro[indoline-3,2'-pyran]-2,6'(3'H)-dione

Base Information

• Chemical Name: benzyl-4',5-dimethylspiro[indoline-3,2'-pyran]-2,6'(3'H)-dione
• CAS No.: 1449481-83-7
• Molecular Formula: C₂₁H₁₉NO₃
• Molecular Weight: 333.387
• Mol file: 1449481-83-7.mol

Synonyms:benzyl-4',5-dimethylspiro[indoline-3,2'-pyran]-2,6'(3'H)-dione

Chemical Property of benzyl-4',5-dimethylspiro[indoline-3,2'-pyran]-2,6'(3'H)-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl-4',5-dimethylspiro[indoline-3,2'-pyran]-2,6'(3'H)-dione

There total 2 articles about benzyl-4',5-dimethylspiro[indoline-3,2'-pyran]-2,6'(3'H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1-benzyl-5-methylindoline-2,3-dione (99448-75-6) + α-bromo-β-methyl-crotonaldehyde (31058-93-2) → benzyl-4',5-dimethylspiro[indoline-3,2'-pyran]-2,6'(3'H)-dione (1449481-83-7)

Guidance literature:

With caesium carbonate; 1,3-bis(mesityl)imidazolium chloride; In tetrahydrofuran; at 25 ℃;

DOI:10.1002/chem.201202655

Reference yield: 77.0%

1-benzyl-5-methylindoline-2,3-dione (99448-75-6) + 3,3-dimethyl acrylaldehyde (107-86-8) → benzyl-4',5-dimethylspiro[indoline-3,2'-pyran]-2,6'(3'H)-dione (1449481-83-7)

Guidance literature:

With 3,5,3',5'-tetra-tert-butyl-4,4'-diphenoquinone; C₅H₉N₂S₂⁽¹⁺⁾*Cl^(1-); caesium carbonate; In tetrahydrofuran; at 25 ℃;

DOI:10.1039/c3ob42008f

upstream raw materials:

1-benzyl-5-methylindoline-2,3-dione

α-bromo-β-methyl-crotonaldehyde

3,3-dimethyl acrylaldehyde