7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride

Base Information

• Chemical Name: 7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride
• CAS No.: 111758-82-8
• Molecular Formula: C₁₁H₁₅NO*ClH
• Molecular Weight: 213.707
• Hs Code.: 2922299090
• European Community (EC) Number: 835-695-7
• DSSTox Substance ID: DTXSID60603359
• Mol file: 111758-82-8.mol

Synonyms:111758-82-8;7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride;7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylamine hydrochloride;7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine HCl;7-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride;XEVOHMWMOYSWMZ-UHFFFAOYSA-N;SCHEMBL2688145;DTXSID60603359;MFCD08544187;AKOS016001459;SB78824;SB79092;EN300-99246;N12846;A853552;Z1331054615;7-methoxy-1,2,3,4-tetrahydro-1-naphthylamine hydrochloride;7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-aminehydrochloride;7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride(1:x);7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine--hydrogen chloride (1/1);840531-31-9

Chemical Property of 7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride

Chemical Property:

• Vapor Pressure: 0.0002mmHg at 25°C
• Boiling Point: 322.7°C at 760 mmHg
• Flash Point: 149°C
• PSA: 35.25000
• LogP: 3.53360
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 213.0920418
• Heavy Atom Count: 14
• Complexity: 172

Purity/Quality:

97% ^*data from raw suppliers

7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC2=C(CCCC2N)C=C1.Cl

Technology Process of 7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride

There total 4 articles about 7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C16H23NO3 (305797-92-6) → 7-methoxy-1,2,3,4-tetrahydro-[1]naphthylamine; hydrochloride (111758-82-8)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 20h;

Reference yield: 98.0%

(Z)-tert-butyl 7-methoxy-3,4-dihydronaphthalen-1(2H)-ylidenecarbamate (1374781-09-5) → 7-methoxy-1,2,3,4-tetrahydro-[1]naphthylamine; hydrochloride (111758-82-8)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 20h;

Reference yield:

1,2,3,4-tetrahydro-1-isonitroso-7-methoxynaphthalene → 7-methoxy-1,2,3,4-tetrahydro-[1]naphthylamine; hydrochloride (111758-82-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrogen; ammonia / Raney nickel / methanol / 3 h / 2585.81 Torr

1.2: 1 h / 20 °C

2.1: hydrogenchloride / 1,4-dioxane / 20 h / 20 °C

With hydrogenchloride; ammonia; hydrogen; Raney nickel; In 1,4-dioxane; methanol;

upstream raw materials:

7-Methoxy-1-tetralone

C₁₆H₂₃NO₃

(Z)-tert-butyl 7-methoxy-3,4-dihydronaphthalen-1(2H)-ylidenecarbamate