4-(2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl)-N'-(6-methylpyridin-3-yl)benzamidine

Base Information

• Chemical Name: 4-(2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl)-N'-(6-methylpyridin-3-yl)benzamidine
• CAS No.: 1001014-38-5
• Molecular Formula: C₂₁H₂₀N₆
• Molecular Weight: 356.43

Synonyms:4-(2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl)-N'-(6-methylpyridin-3-yl)benzamidine

Chemical Property of 4-(2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl)-N'-(6-methylpyridin-3-yl)benzamidine

Chemical Property:

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Technology Process of 4-(2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl)-N'-(6-methylpyridin-3-yl)benzamidine

There total 1 articles about 4-(2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl)-N'-(6-methylpyridin-3-yl)benzamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-(2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl)-N'-(6-methylpyridin-3-yl)benzamidine (1001014-38-5)

Guidance literature:

Reference yield:

2-bromo-1-thiazol-2-yl-ethanone (3292-77-1) + 4-(2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl)-N'-(6-methylpyridin-3-yl)benzamidine (1001014-38-5) → 2-ethyl-3-(4-(1-(6-methylpyridin-3-yl)-4-(thiazol-2-yl)-1H-imidazol-2-yl)phenyl)-3H-imidazo[4,5-b]pyridine

Guidance literature:

2-bromo-1-thiazol-2-yl-ethanone; 4-(2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl)-N'-(6-methylpyridin-3-yl)benzamidine; With sodium hydrogencarbonate; In isopropyl alcohol; at 90 ℃; for 2h;

With acetic acid; at 90 ℃; for 0.25h;

With ammonia; water; In methanol; dichloromethane;

Reference yield:

4-(2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl)-N'-(6-methylpyridin-3-yl)benzamidine (1001014-38-5) + 2-bromo-1-(5-methyl-thiazol-2-yl)-ethanone (220270-61-1) → 2-ethyl-3-(4-(1-(6-methylpyridin-3-yl)-4-(5-methylthiazol-2-yl)-1H-imidazol-2-yl)phenyl)-3H-imidazo[4,5-b]pyridine

Guidance literature:

4-(2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl)-N'-(6-methylpyridin-3-yl)benzamidine; 2-bromo-1-(5-methyl-thiazol-2-yl)-ethanone; With sodium hydrogencarbonate; In isopropyl alcohol; at 90 ℃; for 2h;

With acetic acid; at 90 ℃; for 2.33333h;

With ammonia; water; In methanol; dichloromethane;

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