2-chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine

Base Information

Chemical Name:2-chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine
CAS No.:76780-97-7
Molecular Formula:C₇H₈ClN₃
Molecular Weight:169.614
Hs Code.:2933998090
DSSTox Substance ID:DTXSID00437130
Mol file:76780-97-7.mol

Synonyms:76780-97-7;2-chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine;2-Chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine;SCHEMBL9267023;DTXSID00437130;MFCD18651772;AKOS006316694;BF-0715;CS-0217287;FT-0682900;E85066;EN300-7285729;J-508923;4-Amino-2-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine 95+%

Suppliers and Price of 2-chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine >95%
500mg
$ 501.00

Matrix Scientific
2-Chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine >95%
5g
$ 2695.00

Matrix Scientific
2-Chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine >95%
1g
$ 770.00

Crysdot
2-Chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine 95+%
1g
$ 762.00

AK Scientific
2-Chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine
500mg
$ 726.00

Total 9 raw suppliers

Chemical Property of 2-chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:169.0406750
Heavy Atom Count:11
Complexity:153

Purity/Quality:

99%, ^*data from raw suppliers

2-Chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C1)N=C(N=C2N)Cl

Technology Process of 2-chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine

There total 5 articles about 2-chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 5466-43-3
2,4-dichloro-6,7-dihydro-5H-cyclopentapyrimidine

: 76780-97-7
(2-chloro-6,7-dihydro-5H-cyclopentapyrimidin-4-yl)amine

Guidance literature:: With ammonium hydroxide; In ethanol; at 100 ℃;

Reference yield:

: 611-10-9
2-ethoxycarbonyl-1-cyclopentanone

: 76780-97-7
(2-chloro-6,7-dihydro-5H-cyclopentapyrimidin-4-yl)amine

Guidance literature:: Multi-step reaction with 3 steps

1: 40 g / ethanol / 5 h / 160 °C

2: 19 g / POCl₃ / 2 h / Heating

3: 8 g / 28percent NH₄OH / ethanol / 14 h / 40 °C

With ammonium hydroxide; trichlorophosphate; In ethanol;
DOI:10.1021/jm00048a018

Reference yield:

: 5466-00-2
6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diol

: 76780-97-7
(2-chloro-6,7-dihydro-5H-cyclopentapyrimidin-4-yl)amine

Guidance literature:: Multi-step reaction with 2 steps

1: 19 g / POCl₃ / 2 h / Heating

2: 8 g / 28percent NH₄OH / ethanol / 14 h / 40 °C

With ammonium hydroxide; trichlorophosphate; In ethanol;
DOI:10.1021/jm00048a018